SSTR4
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Official Full Name
somatostatin receptor 4 -
Overview
transmembrane receptor for somatostatin; coupled to a G-protein which inhibits adenylyl cyclase; may also activate the mitogen-activated protein (MAP) kinase cascade -
Synonyms
SSTR4;somatostatin receptor 4;somatostatin receptor type 4;SS 4R;SS4R;SST R4;SSTR 4;SS4-R;SS-4-R;Somatostatin receptor subtype 4 Rattus norvegicus Sprague-Dawley major hippocampal somatostatin receptor (SSTR4) mRNA;Smstr4
Recombinant Proteins
- Chicken
- Rat
- Mus musculus
- Human
- Mammalian Cell
- E.coli expression system
- HEK293
- His
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| SSTR4-3163C | Recombinant Chicken SSTR4 | Mammalian Cell | Chicken | His |
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| SSTR4-5763R | Recombinant Rat SSTR4 Protein | Mammalian Cell | Rat | His |
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| RFL12898MF | Recombinant Full Length Mouse Somatostatin Receptor Type 4(Sstr4) Protein, His-Tagged | E.coli expression system | Mus musculus | His | Full L. Full Length (1-384) |
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| RFL21724HF | Recombinant Full Length Human Somatostatin Receptor Type 4(Sstr4) Protein, His-Tagged | E.coli expression system | Human | His | Full L. Full Length (1-388) |
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| RFL24711RF | Recombinant Full Length Rat Somatostatin Receptor Type 4(Sstr4) Protein, His-Tagged | E.coli expression system | Rat | His | Full L. Full Length (1-384) |
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| SSTR4-5422R | Recombinant Rat SSTR4 Protein, His (Fc)-Avi-tagged | HEK293 | Rat | His&Fc&Avi |
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| SSTR4-5422R-B | Recombinant Rat SSTR4 Protein Pre-coupled Magnetic Beads | HEK293 | Rat |
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Involved Pathway
SSTR4 involved in several pathways and played different roles in them. We selected most pathways SSTR4 participated on our site, such as Class A/1 (Rhodopsin-like receptors),G alpha (i) signalling events,GPCR downstream signaling, which may be useful for your reference. Also, other proteins which involved in the same pathway with SSTR4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| GPCR ligand binding | S1PR1,OPN1SW1,GPR55,GPR31B,MLN,OPN1LW,TAAR1,GPR55A,ACKR4,GNB5B |
| GPCRs, Class A Rhodopsin-like | SSTR1,OPN4,OR10A5,LTB4R,GPR68,GPR4,FFAR3,GPR63,OR3A4P,CCR7 |
| Peptide ligand-binding receptors | INSL3,PNOCB,PROKR1A,PRLH,GPR37B,SST,PROK1,PROKR2,CCL35.2,QRFPR |
| Class A/1 (Rhodopsin-like receptors) | AGTR2,ADORA2B,EDNRB,GPR39,CCL27,OPN1SW,OPN4,PNOC,FPR-RS4,SST1.1 |
| GPCR downstream signaling | TAS2R3,OR52J3,FGD4A,EDNRA,RGS6,ARHGAP4,ADCYAP1R1,ARHGEF25,NPB,S1PR5B |
| G alpha (i) signalling events | RLN3,RGS6,RGS12,CNR1,PENKA,ADRA2C,PYYA,OXGR1A.3,GPR18,OXER1 |
| Peptide GPCRs | TAC4,CXCR6,CX3CR1,SSTR1,SSTR5 |
| Neuroactive ligand-receptor interaction | GHR,TACR3,CHRM2A,P2RY4,TAAR4,GRIA1A,P2RX3B,GHSRA,TAAR10C,TACR1 |
Protein Function
SSTR4 has several biochemical functions, for example, neuropeptide binding,somatostatin receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by SSTR4 itself. We selected most functions SSTR4 had, and list some proteins which have the same functions with SSTR4. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| somatostatin receptor activity | SSTR5,SSTR2,SSTR3,SSTR1 |
| neuropeptide binding | OPRD1,MRGPRB1,MRGPRX2,PTGDR2,NPBWR2,ADCYAP1R1,MC4R,GPR1,OPRD1A,OPRK1 |
Interacting Protein
SSTR4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SSTR4 here. Most of them are supplied by our site. Hope this information will be useful for your research of SSTR4.
Resources
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References
- Frati, A; Rouzier, R; et al. Expression of Somatostatin Type-2 and-4 Receptor and Correlation with Histological Type in Breast Cancer. ANTICANCER RESEARCH 34:3997-4003(2014).
- Yamamoto, J; Ohnuma, K; et al. Regulation of somatostatin receptor 4-mediated cytostatic effects by CD26 in malignant pleural mesothelioma. BRITISH JOURNAL OF CANCER 110:2232-2245(2014).
