SS18L1
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Official Full Name
synovial sarcoma translocation gene on chromosome 18-like 1 -
Overview
Synovial sarcomas occur most frequently in the extremities around large joints. More than 90% of cases have a recurrent and specific chromosomal translocation, t(X;18)(p11.2;q11.2), in which the 5-prime end of the SS18 gene (MIM 600192) is fused in-frame to the 3-prime end of the SSX1 (MIM 312820), SSX2 (MIM 300192), or SSX4 (MIM 300326) gene. The SS18L1 gene is homologous to SS18. -
Synonyms
SS18L1;synovial sarcoma translocation gene on chromosome 18-like 1;calcium-responsive transactivator;KIAA0693;SS18;SS18-like protein 1;SSXT;synovial sarcoma translocation;SYT homolog 1;CREST;LP2261
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| SS18L1-16021M | Recombinant Mouse SS18L1 Protein | Mammalian Cell | Mouse | His |
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| SS18L1-5751R | Recombinant Rat SS18L1 Protein | Mammalian Cell | Rat | His |
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| SS18L1-5410R | Recombinant Rat SS18L1 Protein, His (Fc)-Avi-tagged | HEK293 | Rat | His&Fc&Avi |
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| SS18L1-5410R-B | Recombinant Rat SS18L1 Protein Pre-coupled Magnetic Beads | HEK293 | Rat |
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| SS18L1-8739M | Recombinant Mouse SS18L1 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| SS18L1-8739M-B | Recombinant Mouse SS18L1 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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Involved Pathway
SS18L1 involved in several pathways and played different roles in them. We selected most pathways SS18L1 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with SS18L1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
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Protein Function
SS18L1 has several biochemical functions, for example, DNA binding,transcription factor activity, sequence-specific DNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SS18L1 itself. We selected most functions SS18L1 had, and list some proteins which have the same functions with SS18L1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| transcription factor activity, sequence-specific DNA binding | MNX1,ZNF83,ZNF19,IKZF5,SKINT8,CDX2,ZNF193,MLXIPL,NFE2,HOXC8A |
| DNA binding | PBX1B,DEK,ISX,ZNF134,NFE2L1B,ATM,PAX2A,LHX6,SALL1,ZFP488 |
Interacting Protein
SS18L1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SS18L1 here. Most of them are supplied by our site. Hope this information will be useful for your research of SS18L1.
Ywhae
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References
- Teyssou, E; Vandenberghe, N; et al. Genetic analysis of SS18L1 in French amyotrophic lateral sclerosis. NEUROBIOLOGY OF AGING 35:-(2014).
- Renton, AE; Traynor, BJ; et al. CRESTing the ALS mountain. NATURE NEUROSCIENCE 16:774-775(2013).
