SRSF12
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Official Full Name
serine/arginine-rich splicing factor 12 -
Synonyms
SRSF12;serine/arginine-rich splicing factor 12;SFRS13B, splicing factor, arginine/serine rich 13B;SFRS19;splicing factor;arginine/serine rich 19;SR splicing factor 12;SRrp35;arginine/serine-rich 13B;arginine/serine-rich 19;FLJ41221;35 kDa SR repressor protein;FLJ14459;FLJ33484;RP11 63L7.3;Serine arginine repressor protein (35 kDa);Serine/arginine rich splicing factor 12;SFRS13B;Splicing factor arginine/serine rich 13B;Splicing factor arginine/serine rich 19;SRS12_HUMAN;splicing factor, arginine/serine-rich 19;splicing factor, arginine/serine-rich 13B;serine-arginine repressor protein (35 kDa);RP11-63L7.3
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| SRSF12-1905HCL | Recombinant Human SFRS13B 293 Cell Lysate | HEK293 | Human | Non |
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| SRSF12-3343H | Recombinant Human SRSF12 Protein, Myc/DDK-tagged, C13 and N15-labeled | HEK293T | Human | Myc&DDK |
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| Srsf12-6137M | Recombinant Mouse Srsf12 Protein, Myc/DDK-tagged | HEK293T | Mouse | Myc&DDK |
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Involved Pathway
SRSF12 involved in several pathways and played different roles in them. We selected most pathways SRSF12 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with SRSF12 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
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Protein Function
SRSF12 has several biochemical functions, for example, RNA binding,RS domain binding,nucleotide binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SRSF12 itself. We selected most functions SRSF12 had, and list some proteins which have the same functions with SRSF12. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| nucleotide binding | FHIT,INSRB,CELF1,SMC5,GRK7A,EIF4H,DIRAS1B,CKMA,KIAA0430,ATP2A2A |
| unfolded protein binding | GRPEL2,CCT5,DNAJA1,CLPXA,HSP90AA1.1,CLGN,CDC37L1,HSP90AB1,AHSP,HTRA2 |
| RNA binding | AGFG1A,HNRNPL2,RPS4Y1,CRNKL1,WDHD1,CSTF3,DDX19A,RPL39L,ZNF385D,RPL26 |
| RS domain binding | LUC7L,SRSF10,SRSF5,SRSF1 |
| poly(A) RNA binding | HNRPDL,SUB1,DDX27,RPS8,DDX54,RPS2,BCCIP,DNM1,LSM8,RTCA |
Interacting Protein
SRSF12 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SRSF12 here. Most of them are supplied by our site. Hope this information will be useful for your research of SRSF12.
SRPK2;CDK6;SRPK1;EIF4A3;MAGOH
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References
- Akula, N; Barb, J; et al. RNA-sequencing of the brain transcriptome implicates dysregulation of neuroplasticity, circadian rhythms and GTPase binding in bipolar disorder. MOLECULAR PSYCHIATRY 19:1179-1185(2014).
- Cyphert, TJ; Suchanek, AL; et al. Starvation actively inhibits splicing of glucose-6-phosphate dehydrogenase mRNA via a bifunctional ESE/ESS element bound by hnRNP K. BIOCHIMICA ET BIOPHYSICA ACTA-GENE REGULATORY MECHANISMS 1829:905-915(2013).
