SRP72
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Official Full Name
signal recognition particle 72kDa -
Overview
This gene encodes the 72 kDa subunit of the signal recognition particle (SRP), a ribonucleoprotein complex that;mediates the targeting of secretory proteins to the endoplasmic reticulum (ER). The SRP complex consists of a 7S RNA;and 6 protein subunits: SRP9, SRP14, SRP19, SRP54, SRP68, and SRP72, that are bound to the 7S RNA as monomers or;heterodimers. SRP has at least 3 distinct functions that can be associated with the protein subunits: signal;recognition, translational arrest, and ER membrane targeting by interaction with the docking protein. Mutations in;this gene are associated with familial bone marrow failure. Alternatively spliced transcript variants encoding;different isoforms have been found for this gene. -
Synonyms
SRP72;signal recognition particle 72kDa;signal recognition particle 72kD;signal recognition particle 72 kDa protein
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| SRP72-1589C | Recombinant Chicken SRP72 | Mammalian Cell | Chicken | His |
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| SRP72-4469R | Recombinant Rhesus monkey SRP72 Protein, His-tagged | Mammalian Cell | Rhesus macaque | His |
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| SRP72-1477HCL | Recombinant Human SRP72 293 Cell Lysate | HEK293 | Human | Non |
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| SRP72-1078H | Recombinant Human SRP72 protein, GST-tagged | E.coli | Human | GST | 2-671aa |
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| SRP72-4285R | Recombinant Rhesus Macaque SRP72 Protein, His (Fc)-Avi-tagged | HEK293 | Rhesus macaque | His&Fc&Avi |
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| SRP72-4285R-B | Recombinant Rhesus Macaque SRP72 Protein Pre-coupled Magnetic Beads | HEK293 | Rhesus macaque |
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Involved Pathway
SRP72 involved in several pathways and played different roles in them. We selected most pathways SRP72 participated on our site, such as Protein export, which may be useful for your reference. Also, other proteins which involved in the same pathway with SRP72 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Protein export | SPCS1,SRP54A,secB,ARXES2,SEC62,IMMP1L,SEC61A1,SEC11A,SPCS2,SRPRB |
Protein Function
SRP72 has several biochemical functions, for example, 7S RNA binding,poly(A) RNA binding,signal recognition particle binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SRP72 itself. We selected most functions SRP72 had, and list some proteins which have the same functions with SRP72. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| 7S RNA binding | PIGC,EXOSC2,SRP9,SRP19,SRP54,SRP14,SRP68,SRP54A |
| signal recognition particle binding | SRPR,SRP68,SRP9 |
| poly(A) RNA binding | ZCCHC11,NOC4L,HIST1H4L,NHP2,TCP1,SAFB,LIN28B,RPL22,DCN,DHX38 |
Interacting Protein
SRP72 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SRP72 here. Most of them are supplied by our site. Hope this information will be useful for your research of SRP72.
HLA-B;PINX1;TULP3;FCHSD2;HSPB1;PYGM;SKIL;1C;NPM1;Eif3a;RPL10;HNRNPU;ORC1;SNW1;BECN1
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References
- Yildirim-Ersoy, F; Ridout, CJ; et al. Detection of physically interacting proteins with the CC and NB-ARC domains of a putative yellow rust resistance protein, Yr10, in wheat. JOURNAL OF PLANT DISEASES AND PROTECTION 118:119-126(2011).
