SRP68

  • Official Full Name

    signal recognition particle 68kDa
  • Overview

    This gene encodes a subunit of the signal recognition particle (SRP). The SRP is a ribonucleoprotein complex that;transports secreted and membrane proteins to the endoplasmic reticulum for processing. The complex includes a 7S RNA;and six protein subunits. The encoded protein is the 68kDa component of the SRP, and forms a heterodimer with the;72kDa subunit that is required for SRP function. Alternatively spliced transcript variants encoding multiple isoforms;have been observed for this gene, and three pseudogenes of this gene are located within the Smith-Magenis syndrome;region on chromosome 17.
  • Synonyms

    SRP68;signal recognition particle 68kDa;signal recognition particle 68 kDa protein;Signal recognition particle 68 kDa;SRP 68;SRP68_HUMAN;68kDA subunit of signal recognition particle

Recombinant Proteins

  • Chicken
  • Zebrafish
  • Mouse
  • Human
  • Mammalian Cell
  • E.coli
  • E. coli
  • HEK293
  • His
  • N-SUMO & N-His
  • N-MBP&C-His
  • His&Fc&Avi
Cat.# Product name Source (Host) Species Tag Protein Length Price
SRP68-1353C Recombinant Chicken SRP68 Mammalian Cell Chicken His
SRP68-1414Z Recombinant Zebrafish SRP68 Mammalian Cell Zebrafish His
SRP68-15992M Recombinant Mouse SRP68 Protein Mammalian Cell Mouse His
SRP68-11H Recombinant Human SRP68 protein, His-SUMO-tagged E.coli Human N-SUMO & N-His 11-580 aa
SRP68-12H Recombinant Human SRP68 protein, MBP&His-tagged E. coli Human N-MBP&C-His Gly11-Gly580
SRP68-8721M Recombinant Mouse SRP68 Protein, His (Fc)-Avi-tagged HEK293 Mouse His&Fc&Avi
SRP68-8721M-B Recombinant Mouse SRP68 Protein Pre-coupled Magnetic Beads HEK293 Mouse

    Involved Pathway

    SRP68 involved in several pathways and played different roles in them. We selected most pathways SRP68 participated on our site, such as Protein export, which may be useful for your reference. Also, other proteins which involved in the same pathway with SRP68 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Protein export SPCS1,SRPR,IMMP1L,SPCS2,SEC63,SPCS3,OXA1L,SEC61AL2,SRP54,SEC61G

    Protein Function

    SRP68 has several biochemical functions, for example, 7S RNA binding,RNA binding,endoplasmic reticulum signal peptide binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SRP68 itself. We selected most functions SRP68 had, and list some proteins which have the same functions with SRP68. You can find most of the proteins on our site.

    Function Related Protein
    RNA binding FBL,EIF4B,CNOT6,DIS3L,ZNF239,SARS,DDX53,HNRPL,RBM18,NOL4
    endoplasmic reticulum signal peptide binding SRP54,SRP54A,PIGC,SRP54B,SRP14
    7S RNA binding SRP19,EXOSC2,SRP54A,SRP14,PIGC,SRP54,SRP72,SRP9
    signal sequence binding AP2B1,AP2M1
    signal recognition particle binding SRP72,SRP9,SRPR
    poly(A) RNA binding SLIRP,SLBP,G3BP1,CCDC86,DUS3L,CIRBP,HSP90AA1,RPP25,UBFD1,DCN

    Interacting Protein

    SRP68 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SRP68 here. Most of them are supplied by our site. Hope this information will be useful for your research of SRP68.

    Resources

    References

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