SRMS
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Official Full Name
src-related kinase lacking C-terminal regulatory tyrosine and N-terminal myristylation sites -
Overview
May be involved in proliferation or differentiation of keratinocytes in the skin. -
Synonyms
SRMS;src-related kinase lacking C-terminal regulatory tyrosine and N-terminal myristylation sites;C20orf148, chromosome 20 open reading frame 148;tyrosine-protein kinase Srms;dJ697K14.1;SRM;C20orf148
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| SRMS-1485H |
Active Recombinant Human SRMS, GST-tagged
|
Sf9 Insect Cell | Human | GST | 215 aa-end |
|
| SRMS-1101H | Recombinant Human Src-Related Kinase Lacking C-terminal Regulatory Tyrosine And N-terminal Myristylation Sites, GST-tagged | Sf9 Insect Cell | Human | GST | 215-end a.a. |
|
| SRMS-2620H | Recombinant Human SRMS, GST-tagged | Insect Cell | Human | GST | 215-488 a.a. |
|
| SRMS-31461TH | Recombinant Human SRMS | Sf9 Insect Cell | Human | Non | 274 amino acids |
|
Involved Pathway
SRMS involved in several pathways and played different roles in them. We selected most pathways SRMS participated on our site, such as Adaptive Immune System,Antigen activates B Cell Receptor (BCR) leading to generation of second messengers,Focal Adhesion, which may be useful for your reference. Also, other proteins which involved in the same pathway with SRMS were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Signaling by the B Cell Receptor (BCR) | STIM1B,IGHM,PIK3AP1 |
| Immune System | RAPGEF4,B2ML,IFIT2,PJA2,LTF,NLRP4B,DYNC1H1,HAVCR2,KIF18A,LGALS3 |
| Focal adhesion | AKT2,MAPK4,ITGA5,CAPN2A,TNK1,RHOAA,CCND2A,EGFRA,LAMA3,ACTG1 |
| Antigen activates B Cell Receptor (BCR) leading to generation of second messengers | IGKV1-5,AHCYL1,STIM1B,BLK,IGKC,IGLC2,IGHM,PIK3AP1,ITPR2,AKR1C1 |
| Adaptive Immune System | AP2A1,KLRF1,DCTN2,DYNC1H1,KIF2C,MGC174152,DNM1,KLC3,OSCAR,RNF144B |
Protein Function
SRMS has several biochemical functions, for example, ATP binding,non-membrane spanning protein tyrosine kinase activity,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SRMS itself. We selected most functions SRMS had, and list some proteins which have the same functions with SRMS. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein tyrosine kinase activity | TTK,PTK6B,NTRK3A,TESK2,EPHA4A,TYK2,TNK2,MAP2K4,ZAP70,AXL |
| non-membrane spanning protein tyrosine kinase activity | JAK2A,PTK2,ABL2,MATK,SRC,FYN,SYK,TYK2,JAK2B,PTK2AB |
| receptor binding | CXCL10,CHRNA10,BLK,LTA,HFE2,DECR2,KCNA5,IDE,NCK1,FGF1A |
| protein binding | C19orf25,PRELID1,NR5A2,H3F3A,ZNF423,PPP1R9A,CD72,POP7,PPP1R13L,IKZF3 |
| ATP binding | NADK2,STK38,ACLY,PCXA,SPEG,MAST4,AKT3A,DDX6,EPHB2B,MAPK8B |
Interacting Protein
SRMS has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SRMS here. Most of them are supplied by our site. Hope this information will be useful for your research of SRMS.
DOK1;HSPB1
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References
- Obradovic, D; Kataranovski, M; et al. Tumor necrosis factor-alfa and interleukin-4 in cerbrospinal fluid and plasma in different clinical forms of multiple sclerosis. VOJNOSANITETSKI PREGLED 69:151-156(2012).
- Kruithof, E; De Rycke, L; et al. Identification of synovial biomarkers of response to experimental treatment in early-phase clinical trials in spondylarthritis. ARTHRITIS AND RHEUMATISM 54:1795-1804(2006).
