SRB4
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Official Full Name
Srb4p -
Overview
SRB4 is a transcription factor that has an important role in basal and activated transcription in vitro and is essential for efficient establishment of the transcription initiation apparatus. The SRB-TBP complex binds specifically to the C-terminal domain of RNA polymerase II (CTD) in forming the transcription initiation complex. -
Synonyms
SRB4;Srb4p;MED17;YER022W;NP_010939.1;Eukaryota;Fungi;Ascomycota;Saccharomycotina (true yeasts);Taphrinomycotina;Schizosaccharomycetes (fission yeasts);Basidiomycota;Agaricomycotina;Tremellomycetes;Pucciniomycotina;Microbotryomycetes
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Involved Pathway
SRB4 involved in several pathways and played different roles in them. We selected most pathways SRB4 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with SRB4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
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Protein Function
SRB4 has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by SRB4 itself. We selected most functions SRB4 had, and list some proteins which have the same functions with SRB4. You can find most of the proteins on our site.
| Function | Related Protein |
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Interacting Protein
SRB4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SRB4 here. Most of them are supplied by our site. Hope this information will be useful for your research of SRB4.
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References
- Tamayo, E; Bernal, G; et al. Mammalian transcription activation domains of VP16, AP2 and CTF activate transcription in a whole cell extract from Schizosaccharomyces pombe through the SRB/mediator. YEAST 22:511-521(2005).
