SQLE
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Official Full Name
squalene epoxidase -
Overview
Squalene epoxidase catalyzes the first oxygenation step in sterol biosynthesis and is thought to be one of the rate-limiting enzymes in this pathway. [provided by RefSeq, Jul 2008] -
Synonyms
SQLE;squalene epoxidase;squalene monooxygenase;SE
Recombinant Proteins
- Human
- Mouse
- Chicken
- Rat
- Cynomolgus
- Mus musculus
- E.coli
- Mammalian Cell
- E.coli expression system
- HEK293
- His
- Non
- His&Fc&Avi
Involved Pathway
SQLE involved in several pathways and played different roles in them. We selected most pathways SQLE participated on our site, such as Steroid biosynthesis,Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with SQLE were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Metabolic pathways | CYP2C38,DHRS3,B3GNT5,ALDH3A2A,ALG11,LASS4,GNSB,ATP6V1C1,POLR2D,MTAP |
| Steroid biosynthesis | CYP51,CYP2R1,SC4MOL,FAXDC2,DHCR7,CELL,DHCR24,CEL.1,SOAT1,FDFT1 |
Protein Function
SQLE has several biochemical functions, for example, flavin adenine dinucleotide binding,squalene monooxygenase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by SQLE itself. We selected most functions SQLE had, and list some proteins which have the same functions with SQLE. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| flavin adenine dinucleotide binding | ACOX3,ACAD11,AOX3L1,DHCR24,ACADVL,DLD,AIFM2,ACAD9,ACADSB,IVD |
| squalene monooxygenase activity | SQLEA |
Interacting Protein
SQLE has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SQLE here. Most of them are supplied by our site. Hope this information will be useful for your research of SQLE.
MARCH6;CREB3;ALDOC;ZNF641
Resources
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References
- Jardel, P; Debiais, C; et al. Ductal carcinoma of the prostate shows a different immunophenotype from high grade acinar cancer. HISTOPATHOLOGY 63:57-63(2013).
