SPRY4
-
Official Full Name
sprouty homolog 4 -
Overview
SPRY4 is an inhibitor of the receptor-transduced mitogen-activated protein kinase (MAPK) signaling pathway. It is;positioned upstream of RAS (see HRAS; MIM 190020) activation and impairs the formation of active GTP-RAS (Leeksma et;al., 2002 (PubMed 12027893)). -
Synonyms
SPRY4;sprouty homolog 4 (Drosophila);protein sprouty homolog 4;spry-4
Recombinant Proteins
- Human
- Mouse
- Chicken
- Zebrafish
- E.coli
- Mammalian Cell
- HEK293
- His
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| SPRY4-2939H | Recombinant Human SPRY4, His-tagged | E.coli | Human | His | 1-165aa | |
| SPRY4-15946M | Recombinant Mouse SPRY4 Protein | Mammalian Cell | Mouse | His |
|
|
| SPRY4-2326H | Recombinant Human SPRY4 protein, His-tagged | E.coli | Human | His | 1-299 a.a. |
|
| SPRY4-3568C | Recombinant Chicken SPRY4 | Mammalian Cell | Chicken | His |
|
|
| SPRY4-9335Z | Recombinant Zebrafish SPRY4 | Mammalian Cell | Zebrafish | His |
|
|
| SPRY4-8690M | Recombinant Mouse SPRY4 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
|
|
| SPRY4-8690M-B | Recombinant Mouse SPRY4 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
|
Involved Pathway
SPRY4 involved in several pathways and played different roles in them. We selected most pathways SPRY4 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with SPRY4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
SPRY4 has several biochemical functions, for example, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SPRY4 itself. We selected most functions SPRY4 had, and list some proteins which have the same functions with SPRY4. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | MAP2K1,PRKAA2,STK11,TCF7,CACNA2D1A,ASB2,SOAT1,CASQ2,RNF31,STAG2 |
Interacting Protein
SPRY4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SPRY4 here. Most of them are supplied by our site. Hope this information will be useful for your research of SPRY4.
CBL;TESK1;ZDHHC17;TNS2;RIN3
Resources
Related Services
Related Products
References
- Gromova, P; Ralea, S; et al. Kit K641E oncogene up-regulates Sprouty homolog 4 and Trophoblast glycoprotein in interstitial cells of Cajal in a murine model of gastrointestinal stromal tumours. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE 13:1536-1548(2009).
