SPIRE1

  • Official Full Name

    spire homolog 1 (Drosophila)

  • Overview

    Spire proteins, such as SPIRE1, are highly conserved between species. They belong to the family of Wiskott-Aldrich;homology region-2 (WH2) proteins, which are involved in actin organization (Kerkhoff et al., 2001 (PubMed;11747823)).

  • Synonyms

    SPIRE1;spire homolog 1 (Drosophila);protein spire homolog 1;KIAA1135;spir 1;MGC150621;MGC150622;Spir1;SPIRE 1;Spire homolog 1;Spir-1
Cat.# Product name Source (Host) Species Tag Protein Length Price
SPIRE1-1507HCL Recombinant Human SPIRE1 293 Cell Lysate HEK293 Human Non

    Involved Pathway

    SPIRE1 involved in several pathways and played different roles in them. We selected most pathways SPIRE1 participated on our site, such as Dorso-ventral axis formation, which may be useful for your reference. Also, other proteins which involved in the same pathway with SPIRE1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Dorso-ventral axis formation ETV7,NOTCH1A,KRAS,NOTCH2,CPEB4,GRB2,NOTCH1B,CPEB2,PIWIL4,GRB2B

    Protein Function

    SPIRE1 has several biochemical functions, for example, actin binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SPIRE1 itself. We selected most functions SPIRE1 had, and list some proteins which have the same functions with SPIRE1. You can find most of the proteins on our site.

    Function Related Protein
    actin binding FLNC,MSN,SYNE1,WIPF2B,VMHC,INPPL1,CLMN,SPTBN2,GBP1,TMOD3

    Interacting Protein

    SPIRE1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SPIRE1 here. Most of them are supplied by our site. Hope this information will be useful for your research of SPIRE1.

    YWHAQ;SFN;k7_vaccw

    Resources

    References

    • Ovsyannikova, IG; Kennedy, RB; et al. Genome-wide association study of antibody response to smallpox vaccine. VACCINE 30:4182-4189(2012).

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