SPIC
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Official Full Name
Spi-C transcription factor (Spi-1/PU.1 related) -
Synonyms
SPIC;Spi-C transcription factor (Spi-1/PU.1 related);transcription factor Spi-C;MGC40611;SPI C;SPI-C
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| SPIC-084H | Recombinant Human SPIC Protein, HIS-tagged | E.coli | Human | HIS |
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| SPIC-1340Z | Recombinant Zebrafish SPIC | Mammalian Cell | Zebrafish | His |
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| SPIC-15881M | Recombinant Mouse SPIC Protein | Mammalian Cell | Mouse | His |
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| SPIC-1516HCL | Recombinant Human SPIC 293 Cell Lysate | HEK293 | Human | Non |
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| SPIC-8644M | Recombinant Mouse SPIC Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| SPIC-8644M-B | Recombinant Mouse SPIC Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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Involved Pathway
SPIC involved in several pathways and played different roles in them. We selected most pathways SPIC participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with SPIC were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
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Protein Function
SPIC has several biochemical functions, for example, RNA polymerase II transcription factor activity, sequence-specific DNA binding,sequence-specific DNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SPIC itself. We selected most functions SPIC had, and list some proteins which have the same functions with SPIC. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| sequence-specific DNA binding | HMX3,ATF5A,HOXD3,FOXB1,HOXA9B,DMRT2B,RORC,GLI1,FOXP3A,FOXI3B |
| RNA polymerase II transcription factor activity, sequence-specific DNA binding | HIF3A,FOXC1A,TAL1,TFDP1A,FOXB1B,FOXA1,SOX8A,TFE3A,ZMYM5,FOXQ1B |
Interacting Protein
SPIC has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SPIC here. Most of them are supplied by our site. Hope this information will be useful for your research of SPIC.
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References
- Geng, SZ; Jiao, XN; et al. Virulence determinants of Salmonella Gallinarum biovar Pullorum identified by PCR signature-tagged mutagenesis and the spiC mutant as a candidate live attenuated vaccine. VETERINARY MICROBIOLOGY 168:388-394(2014).
- Shotland, Y; Kramer, H; et al. The Salmonella SpiC protein targets the mammalian Hook3 protein function to alter cellular trafficking. MOLECULAR MICROBIOLOGY 49:1565-1576(2003).
- Yu, XJ; Ruiz-Albert, J; et al. SpiC is required for secretion of Salmonella Pathogenicity Island 2 type III secretion system proteins. CELLULAR MICROBIOLOGY 4:531-540(2002).
- Chen, HQ; Schifferli, DM; et al. Construction, characterization, and immunogenicity of an attenuated Salmonella enterica serovar typhimurium pgtE vaccine expressing fimbriae with integrated viral epitopes from the spiC promoter. INFECTION AND IMMUNITY 71:4664-4673(2003).
