SPC25
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Official Full Name
SPC25, NDC80 kinetochore complex component -
Overview
This gene encodes a protein that may be involved in kinetochore-microtubule interaction and spindle checkpoint activity. [provided by RefSeq, Jul 2008] -
Synonyms
SPC25;SPC25, NDC80 kinetochore complex component;AD024;SPBC25;hSpc25;kinetochore protein Spc25;2600017H08Rik;spindle pole body component 25 homolog;SPC25, NDC80 kinetochore complex component, homolog
Recombinant Proteins
- Human
- Chicken
- Rat
- Zebrafish
- E.coli
- Mammalian Cell
- HEK293
- His
- Non
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| SPC25-406H | Recombinant Human SPC25 Protein, His-tagged | E.coli | Human | His |
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| SPC25-5206C | Recombinant Chicken SPC25 | Mammalian Cell | Chicken | His |
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| SPC25-5695R | Recombinant Rat SPC25 Protein | Mammalian Cell | Rat | His |
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| SPC25-6631Z | Recombinant Zebrafish SPC25 | Mammalian Cell | Zebrafish | His |
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| SPC25-1527HCL | Recombinant Human SPC25 293 Cell Lysate | HEK293 | Human | Non |
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| SPC25-5354R | Recombinant Rat SPC25 Protein, His (Fc)-Avi-tagged | HEK293 | Rat | His&Fc&Avi |
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| SPC25-5354R-B | Recombinant Rat SPC25 Protein Pre-coupled Magnetic Beads | HEK293 | Rat |
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Involved Pathway
SPC25 involved in several pathways and played different roles in them. We selected most pathways SPC25 participated on our site, such as Cell Cycle,Cell Cycle, Mitotic,M Phase, which may be useful for your reference. Also, other proteins which involved in the same pathway with SPC25 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Mitotic Metaphase and Anaphase | INCENP,NUDC,ZWINT,CENPI,NDEL1,CENPC1,CENPH,MLF1IP,CCDC99,NDC80 |
| Cell cycle | GINS1,YWHABA,TFDP1A,RB1,HIST4H4,HDAC5,BORA,RAD21B,KIF2A,NEK6 |
| Mitotic Anaphase | PDS5A,SKA2,CDCA8,CENPP,TMPO,PMF1,RANGAP1B,KNTC1,B9D2,DSN1 |
| Mitotic Prometaphase | B9D2,DSN1,CCDC99,NDC80,CENPL,SPC24,CENPP,KNTC1,ZWILCH,SGOL1 |
| RHO GTPase Effectors | KLC3,RHPN1,PMF1,ABI1B,KTN1,TAX1BP3,WIPF3,ZWINT,RTKN,ZW10 |
| RHO GTPases Activate Formins | SGOL2,NUF2,RANGAP1B,CCDC99,RHOAE,RCC2,FMNL2,ZWILCH,EVL,NDEL1A |
| Cell Cycle, Mitotic | CDK11B,MYCA,CEP72,DYNC1I2,KIF2A,MAPRE1,FOXM1,TSGA14,RANGAP1B,NUP35 |
| M Phase | ENSA,SPDL1,ZWINT,B9D2,CENPE,CENPO,CLIP1,MASTL,ARPP19A,RANGAP1B |
Protein Function
SPC25 has several biochemical functions, for example, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SPC25 itself. We selected most functions SPC25 had, and list some proteins which have the same functions with SPC25. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | TRAF3IP3,GTPBP4,FAM20C,CDKN1C,JAK2,UVRAG,KCNE2,TXN,UBE2U,PTRF |
Interacting Protein
SPC25 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SPC25 here. Most of them are supplied by our site. Hope this information will be useful for your research of SPC25.
NDC80;SPC24;MIS12;ZWINT
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