SPAG11B
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Official Full Name
sperm associated antigen 11B -
Overview
This gene encodes several androgen-dependent, epididymis-specific secretory proteins. The specific functions of these proteins have not been determined, but they are thought to be involved in sperm maturation. Some of the isoforms contain regions of similarity to beta-defensins, a family of antimicrobial peptides. The gene is located on chromosome 8p23 near the defensin gene cluster. Alternative splicing of this gene results in seven transcript variants encoding different isoforms. Two different N-terminal and five different C-terminal protein sequences are encoded by the splice variants. Two additional variants have been described, but their full length sequences have not been determined. -
Synonyms
SPAG11B;sperm associated antigen 11B;sperm-associated antigen 11B;EDDM2B;EP2;EP2C;EP2D;epididymal protein 2B;HE2;Epididymal protein 2;HE2C;Protein EP2;SPAG11;Sperm antigen HE2;Sperm associated antigen 11;human epididymis-specific protein 2
Recombinant Proteins
- Rhesus macaque
- Rat
- Human
- Mammalian Cells
- HEK293
- His
- Myc&DDK
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| SPAG11B-4421R | Recombinant Rhesus monkey SPAG11B Protein, His-tagged | Mammalian Cells | Rhesus macaque | His |
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| SPAG11B-5680R | Recombinant Rat SPAG11B Protein | Mammalian Cells | Rat | His |
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| SPAG11B-2509H | Recombinant Human SPAG11B Protein, MYC/DDK-tagged | HEK293 | Human | Myc&DDK |
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| SPAG11B-2872H | Recombinant Human SPAG11B Protein, Myc/DDK-tagged, C13 and N15-labeled | HEK293 | Human | Myc&DDK |
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| SPAG11B-4237R | Recombinant Rhesus Macaque SPAG11B Protein, His (Fc)-Avi-tagged | HEK293 | Rhesus macaque | His&Fc&Avi |
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| SPAG11B-4237R-B | Recombinant Rhesus Macaque SPAG11B Protein Pre-coupled Magnetic Beads | HEK293 | Rhesus macaque |
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| SPAG11B-5339R | Recombinant Rat SPAG11B Protein, His (Fc)-Avi-tagged | HEK293 | Rat | His&Fc&Avi |
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| SPAG11B-5339R-B | Recombinant Rat SPAG11B Protein Pre-coupled Magnetic Beads | HEK293 | Rat |
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Involved Pathway
SPAG11B involved in several pathways and played different roles in them. We selected most pathways SPAG11B participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with SPAG11B were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
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Protein Function
SPAG11B has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by SPAG11B itself. We selected most functions SPAG11B had, and list some proteins which have the same functions with SPAG11B. You can find most of the proteins on our site.
| Function | Related Protein |
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Interacting Protein
SPAG11B has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SPAG11B here. Most of them are supplied by our site. Hope this information will be useful for your research of SPAG11B.
Resources
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References
- Narmadha, G; Yenugu, S; et al. Molecular modeling of the human sperm associated antigen 11 B (SPAG11B) proteins. SYSTEMS BIOLOGY IN REPRODUCTIVE MEDICINE 61:78-88(2015).
