SP2

  • Official Full Name

    Sp2 transcription factor

  • Overview

    This gene encodes a member of the Sp subfamily of Sp/XKLF transcription factors. Sp family proteins are sequence-specific DNA-binding proteins characterized by an amino-terminal trans-activation domain and three carboxy-terminal zinc finger motifs. This protein contains the least conserved DNA-binding domain within the Sp subfamily of proteins, and its DNA sequence specificity differs from the other Sp proteins. It localizes primarily within subnuclear foci associated with the nuclear matrix, and can activate or in some cases repress expression from different promoters.

  • Synonyms

    SP2;Sp2 transcription factor;transcription factor Sp2;KIAA0048;OTTHUMP00000196580;SP2_HUMAN;SPECIFICITY PROTEIN 2

Recombinant Proteins

  • Mouse
  • Human
  • Rhesus macaque
  • Zebrafish
  • Mammalian Cell
  • Wheat Germ
  • HEK293
  • In Vitro Cell Free System
  • His
  • Non
  • His&Fc&Avi
Cat.# Product name Source (Host) Species Tag Protein Length Price
SP2-15793M Recombinant Mouse SP2 Protein Mammalian Cell Mouse His
SP2-31434TH Recombinant Human SP2 Wheat Germ Human Non 249 amino acids
SP2-31435TH Recombinant Human SP2 Wheat Germ Human Non 91 amino acids
SP2-4418R Recombinant Rhesus monkey SP2 Protein, His-tagged Mammalian Cell Rhesus macaque His
SP2-5794Z Recombinant Zebrafish SP2 Mammalian Cell Zebrafish His
SP2-1676HCL Recombinant Human SP2 cell lysate Human Non
SP2-4234R Recombinant Rhesus Macaque SP2 Protein, His (Fc)-Avi-tagged HEK293 Rhesus macaque His&Fc&Avi
SP2-4234R-B Recombinant Rhesus Macaque SP2 Protein Pre-coupled Magnetic Beads HEK293 Rhesus macaque
SP2-489HF Recombinant Full Length Human SP2 Protein In Vitro Cell Free System Human Full L. 249 amino acids
SP2-8596M Recombinant Mouse SP2 Protein, His (Fc)-Avi-tagged HEK293 Mouse His&Fc&Avi
SP2-8596M-B Recombinant Mouse SP2 Protein Pre-coupled Magnetic Beads HEK293 Mouse

    Involved Pathway

    SP2 involved in several pathways and played different roles in them. We selected most pathways SP2 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with SP2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein

    Protein Function

    SP2 has several biochemical functions, for example, DNA binding,RNA polymerase II transcription factor activity, sequence-specific DNA binding,histone deacetylase binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SP2 itself. We selected most functions SP2 had, and list some proteins which have the same functions with SP2. You can find most of the proteins on our site.

    Function Related Protein
    DNA binding ZNF529,ZNF710,MYC,NEUROD6,DLX6A,MYBL2B,CREBZF,MIER1,TGIF2,ZFP579
    protein binding OTULIN,CCDC106,TMEM185A,ZNF543,IWS1,IL11,WIPF1,NEDD8,MORF4L1,P2RX4
    histone deacetylase binding DDX20,NIPBL,HDAC9,NKX3-1,RAD9A,TOP2B,HIC1,HDAC1,YY1,NR2E1
    RNA polymerase II transcription factor activity, sequence-specific DNA binding SP4,FOXH1,SOX14,ZMYM5,HIF1AL,ATF5,TFDP2,SIM1A,FOXM1,ATF4B2
    metal ion binding ZNF557,PRKCBP1L,CENPT,JUB,RPS27A,A3GALT2,TSSK1,NT5DC3,ZFP91,PFKM

    Interacting Protein

    SP2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SP2 here. Most of them are supplied by our site. Hope this information will be useful for your research of SP2.

    BANP;MCM7;FHL2

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