SOX9A
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Official Full Name
SRY-box containing gene 9a -
Synonyms
SOX9A;SRY-box containing gene 9a;transcription factor SOX-9;Transcription factor sox9a;HMG box transcription factor Sox9a;Jef;Jellyfish;SRY box containing gene 9a;wu:fj17b12;zgc:111921
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| SOX9A-9180Z | Recombinant Zebrafish SOX9A | Mammalian Cell | Zebrafish | His |
|
Involved Pathway
SOX9A involved in several pathways and played different roles in them. We selected most pathways SOX9A participated on our site, such as Deactivation of the beta-catenin transactivating complex,Endochondral Ossification,Signal Transduction, which may be useful for your reference. Also, other proteins which involved in the same pathway with SOX9A were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| TCF dependent signaling in response to WNT | KREMEN1,TLE3B,SOX32,TNKS,RSPO2,BCL9L,LEO1,LGR6,RSPO1,USP34 |
| Endochondral Ossification | ADAMTS5,FRZB,DDR2,IFT88,PTHLH,CST5,MGP,COL10A1A,PTHLHA,NKX3-2 |
| canonical wnt - zebrafish | SP5L,RHOUA,HOXB1B,VENT,CAMK1GA,EVE1,TWIST1A,OTX1B,BIRC5B,IRX3A |
| Signal Transduction | RNF146,CRABP1,RGS20,PLEKHG2,S1PR3,GPR161,ARHGAP40,CRABP2B,QRFP,ARHGEF25 |
| Deactivation of the beta-catenin transactivating complex | CBY1,CTBP1,PYGO2,TLE2,SOX9B,SOX13,PYGO1,TLE4,SRY,TLE3B |
| Signaling by Wnt | RYK,WIF1,PYGO2,RSPO3,FAM123B,KLHL12,LGR4,RSPO1,RSPO2,CCDC88C |
Protein Function
SOX9A has several biochemical functions, for example, RNA polymerase II transcription factor activity, sequence-specific DNA binding,chromatin binding,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SOX9A itself. We selected most functions SOX9A had, and list some proteins which have the same functions with SOX9A. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| RNA polymerase II transcription factor activity, sequence-specific DNA binding | ELF2A,TRP53,SOX5,FOXJ1,PAX6A,ETV2,RUNX2B,TAL1,PLAGL2,FOXR2 |
| chromatin binding | NFKB1,CHD8,POLD1,TDRD3,ZFP354B,GABPA,APITD1,NAP1L2,COQ7,STAG1 |
| protein binding | CNOT8,GMDS,ZNF114,KIF5A,CARD10,RXRA,ZNF266,BCL2L16,HPCAL1,MARCKSL1 |
Interacting Protein
SOX9A has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SOX9A here. Most of them are supplied by our site. Hope this information will be useful for your research of SOX9A.
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References
- Koskinen, J; Karlsson, J; et al. Sox9a regulation of ff1a in zebrafish (Danio rerio) suggests an involvement of ff1a in cartilage development. COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY A-MOLECULAR & INTEGRATIVE PHYSIOLOGY 153:39-43(2009).
