SOX11
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Official Full Name
SRY (sex determining region Y)-box 11 -
Overview
This intronless gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins. The protein may function in the developing nervous system and play a role in tumorigenesis. -
Synonyms
SOX11;SRY (sex determining region Y)-box 11;transcription factor SOX-11;SRY related HMG box gene 11;SRY (sex determining region Y) box 11;SRY-related HMG-box gene 11;SRY (sex-determining region Y)-box 11
Recombinant Proteins
- Mouse
- Rat
- Chicken
- Human
- Mammalian Cell
- HEK293
- E.coli
- E. coli
- His
- Non
- His&GST
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| SOX11-15773M | Recombinant Mouse SOX11 Protein | Mammalian Cell | Mouse | His |
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| SOX11-5676R | Recombinant Rat SOX11 Protein | Mammalian Cell | Rat | His |
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| SOX11-6742C | Recombinant Chicken SOX11 | Mammalian Cell | Chicken | His |
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| SOX11-1564HCL | Recombinant Human SOX11 293 Cell Lysate | HEK293 | Human | Non |
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| SOX11-2089H | Recombinant Human SOX11 Protein, His&GST-tagged | E.coli | Human | His&GST | Met1-Glu224 |
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| SOX11-22H | Recombinant Human SOX11 Protein, His tagged | E. coli | Human | His |
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| SOX11-5335R | Recombinant Rat SOX11 Protein, His (Fc)-Avi-tagged | HEK293 | Rat | His&Fc&Avi |
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| SOX11-5335R-B | Recombinant Rat SOX11 Protein Pre-coupled Magnetic Beads | HEK293 | Rat |
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| SOX11-8584M | Recombinant Mouse SOX11 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| SOX11-8584M-B | Recombinant Mouse SOX11 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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Involved Pathway
SOX11 involved in several pathways and played different roles in them. We selected most pathways SOX11 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with SOX11 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
SOX11 has several biochemical functions, for example, RNA polymerase II core promoter sequence-specific DNA binding,RNA polymerase II transcription coactivator activity,enhancer sequence-specific DNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SOX11 itself. We selected most functions SOX11 had, and list some proteins which have the same functions with SOX11. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| enhancer sequence-specific DNA binding | KLF7B,GATA4,GATA3,SOX9,GATA2,TFAP2B,LDB1,TWIST1B,XBP1,FOXN4 |
| transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding | HOXC11,ELF3,SRF,MEF2B,CDX4,TP53,FOXL2,FUBP3,POU2F2,FOSL1 |
| RNA polymerase II transcription coactivator activity | HYAL2,ISL1,PITX2,SMARCA4,MED12,MYOCD,NCOA1,POU3F2,SOX12,RERE |
| transcription regulatory region sequence-specific DNA binding | CREB3L3,BACH1B,DDIT3,KDM3A,HIF1AL,SOX2,ARNTL1A,MKL1,SUV39H1,NFE2L2 |
| transcription factor activity, sequence-specific DNA binding | RFX5,ZNF26,TCF7L2,DDIT3,PRRX2,PCGF6,UBN2B,POU2F1A,HNF1BA,HER5 |
| translation factor activity, RNA binding | PPP1R2P9,GTF2H2,EEF1D,EIF4G3,CPEB1A,EIF5,GTF2H3,CPEB2,EIF4A1,EIF4G1 |
| RNA polymerase II core promoter sequence-specific DNA binding | STAT6,ZFP335,NFIL3,PAX8,YAP1,TCF7L2,SMAD5,HEYL,FOS,SUZ12 |
Interacting Protein
SOX11 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SOX11 here. Most of them are supplied by our site. Hope this information will be useful for your research of SOX11.
Resources
Research Area
Cancer Stem Cell Transcription FactorsMesenchymal Stem Cell Transcription Factors
Neural Stem Cell Markers
Related Services
Related Products
References
- Zhang, YH; Liu, J; et al. The Role of SOX11 Immunostaining in Confirming the Diagnosis of Mantle Cell Lymphoma on Fine-Needle Aspiration Samples. CANCER CYTOPATHOLOGY 122:892-897(2014).
- Nakashima, MO; Durkin, L; et al. Utility and Diagnostic Pitfalls of SOX11 Monoclonal Antibodies in Mantle Cell Lymphoma and Other Lymphoproliferative Disorders. APPLIED IMMUNOHISTOCHEMISTRY & MOLECULAR MORPHOLOGY 22:720-727(2014).
