SOCS5
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Official Full Name
suppressor of cytokine signaling 5 -
Overview
The protein encoded by this gene contains a SH2 domain and a SOCS BOX domain. The protein thus belongs to the suppressor of cytokine signaling (SOCS) family, also known as STAT-induced STAT inhibitor (SSI) protein family. SOCS family members are known to be cytokine-inducible negative regulators of cytokine signaling. The specific function of this protein has not yet been determined. Two alternatively spliced transcript variants encoding an identical protein have been reported. -
Synonyms
SOCS5;suppressor of cytokine signaling 5;CIS6;Cish5;CISH6;KIAA0671;SOCS 5;CIS-6;cytokine-inducible SH2 protein 6;cytokine-inducible SH2-containing protein 5;SOCS-5
Recombinant Proteins
- Mouse
- Chicken
- Rhesus macaque
- Human
- Mammalian Cell
- E.coli
- HEK293
- His
- Non
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| SOCS5-15746M | Recombinant Mouse SOCS5 Protein | Mammalian Cell | Mouse | His |
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| SOCS5-3841C | Recombinant Chicken SOCS5 | Mammalian Cell | Chicken | His |
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| SOCS5-4404R | Recombinant Rhesus monkey SOCS5 Protein, His-tagged | Mammalian Cell | Rhesus macaque | His |
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| SOCS5-552H | Recombinant Human SOCS5 Protein, His-tagged | E.coli | Human | His |
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| SOCS5-1578HCL | Recombinant Human SOCS5 293 Cell Lysate | HEK293 | Human | Non |
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| SOCS5-1579HCL | Recombinant Human SOCS5 293 Cell Lysate | HEK293 | Human | Non |
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| SOCS5-4220R | Recombinant Rhesus Macaque SOCS5 Protein, His (Fc)-Avi-tagged | HEK293 | Rhesus macaque | His&Fc&Avi |
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| SOCS5-4220R-B | Recombinant Rhesus Macaque SOCS5 Protein Pre-coupled Magnetic Beads | HEK293 | Rhesus macaque |
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| SOCS5-8565M | Recombinant Mouse SOCS5 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| SOCS5-8565M-B | Recombinant Mouse SOCS5 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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Involved Pathway
SOCS5 involved in several pathways and played different roles in them. We selected most pathways SOCS5 participated on our site, such as Jak-STAT signaling pathway,Prolactin signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with SOCS5 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Jak-STAT signaling pathway | IL20RB,JAK2B,CRFB4,IFNE,JAK2A,IL5RA,IFNW1,PIK3R3,CISH,GM13305 |
| Prolactin signaling pathway | FOXO3,PRL,PIK3R2,STAT5A,PRP2,SOCS3,AKT2,PIK3R3,HRAS,MAPK10 |
Protein Function
SOCS5 has several biochemical functions, for example, epidermal growth factor receptor binding,protein binding,receptor tyrosine kinase binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SOCS5 itself. We selected most functions SOCS5 had, and list some proteins which have the same functions with SOCS5. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | VPS16,UPP2,Trl,CSDC2,PTPRM,COL17A1,SIRT3,SLX4,TIFA,ANXA7 |
| receptor tyrosine kinase binding | DNAJA3,PCNA,FIZ1,DOCK4,Flt3l,FNTA,NRG3,NCK1,MYOC,GNB2L1 |
| epidermal growth factor receptor binding | SHC1,ATXN2,FAM83B,FER,TGFA,HBEGFA,SNX2,SNX4,HBEGF,EPGN |
Interacting Protein
SOCS5 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SOCS5 here. Most of them are supplied by our site. Hope this information will be useful for your research of SOCS5.
MET;KIT;PPP5C;CASP3;TCEB1;TMBIM1;npm_alk
SOCS5 Related Signal Pathway
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References
