SNTB2
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Official Full Name
syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2) -
Overview
Dystrophin is a large, rod-like cytoskeletal protein found at the inner surface of muscle fibers. Dystrophin is missing in Duchenne Muscular Dystrophy patients and is present in reduced amounts in Becker Muscular Dystrophy patients. The protein encoded by this gene is a peripheral membrane protein found associated with dystrophin and dystrophin-related proteins. This gene is a member of the syntrophin gene family, which contains at least two other structurally-related genes. -
Synonyms
SNTB2;syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2);D16S2531E, SNT2B2, SNTL, syntrophin, beta 2 (dystrophin associated protein A1, 59kD, basic component 2);beta-2-syntrophin;EST25263;SNT3;Syntrophin like;59 kDa dystrophin associated protein A1 basic component 2;Basic beta 2 syntrophin;Beta 2 syntrophin;D16S2531E;Dystrophin associated protein A1 59kD basic component 2;SNT2B2;SNTL;Syntrophin 3;Syntrophin beta 2 (dystrophin associated protein A1 59kDa basiccomponent 2);syntrophin-3;59 kDa dystrophin-associated protein A1 basic component 2;dystrophin-associated protein A1, 59kD, basic component 2
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
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| SNTB2-2853H | Recombinant Human SNTB2, His-tagged | E.coli | Human | His | 1-300aa |
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| SNTB2-1657HCL | Recombinant Human SNTB2 cell lysate | Human | Non |
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| SNTB2-2251H | Recombinant Human SNTB2 Protein, MYC/DDK-tagged | HEK293 | Human | Myc&DDK |
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| Sntb2-6013M | Recombinant Mouse Sntb2 Protein, Myc/DDK-tagged | HEK293T | Mouse | Myc&DDK |
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| SNTB2-875H | Recombinant Human SNTB2 Protein, Myc/DDK-tagged, C13 and N15-labeled | HEK293T | Human | Myc&DDK |
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Involved Pathway
SNTB2 involved in several pathways and played different roles in them. We selected most pathways SNTB2 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with SNTB2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
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Protein Function
SNTB2 has several biochemical functions, for example, actin binding,calmodulin binding,poly(A) RNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SNTB2 itself. We selected most functions SNTB2 had, and list some proteins which have the same functions with SNTB2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| actin binding | Fert2,GSN,DAAM1B,NRAP,MYH9,SPTB,CNN2,MYO7A,PIP,KPTN |
| structural molecule activity | CLDN16,CLDN14,PRPH,SNTB1,IVL,TUBG2,KRTAP3-3,NUMA1,NCR3LG1,CLDNB |
| protein binding | CDKN3,CD40,MRPL23,USH1G,SLC2A1,FAM131B,SMARCA2,RHOXF2,KLF2,VASH1 |
| poly(A) RNA binding | CALR,KPNA2,CELF2,NAT10,SFRS9,MAGOH2,CCT3,R3HDM2,NCBP1,RPL5 |
| calmodulin binding | STRN,NOS3,MYO7A,TRPV5,KCNN1A,CASK,CAMK2G,NRGNA,GM101,CTH |
Interacting Protein
SNTB2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SNTB2 here. Most of them are supplied by our site. Hope this information will be useful for your research of SNTB2.
ABCA1;Dlg4;PTPRN;CASK;DMD;UTRN;p83954_torca;MARK2;ERBB4;pi3p;LIN7A;Lin7c;MCM7;ZMYM1;Flnb;Pxdc1;SAV1
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References
- Hebel, T; Eisinger, K; et al. Lipid abnormalities in alpha/beta2-syntrophin null mice are independent from ABCA1. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS 1851:527-536(2015).
- Wang, Z; Guo, D; et al. Integrated Analysis of Microarray Data of Atherosclerotic Plaques: Modulation of the Ubiquitin-Proteasome System. PLOS ONE 9:-(2014).
