SNTB1
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Official Full Name
syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) -
Overview
Dystrophin is a large, rod-like cytoskeletal protein found at the inner surface of muscle fibers. Dystrophin is missing in Duchenne Muscular Dystrophy patients and is present in reduced amounts in Becker Muscular Dystrophy patients. The protein encoded by this gene is a peripheral membrane protein found associated with dystrophin and dystrophin-related proteins. This gene is a member of the syntrophin gene family, which contains at least two other structurally-related genes. -
Synonyms
SNTB1;syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1);SNT2B1, syntrophin, beta 1 (dystrophin associated protein A1, 59kD, basic component 1);beta-1-syntrophin;59 DAP;A1B;BSYN2;SNT2;tax interaction protein 43;TIP 4
Recombinant Proteins
- Chicken
- Mouse
- Zebrafish
- Human
- Mammalian Cells
- E.coli
- HEK293
- His
- His&T7
- Myc&DDK
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| SNTB1-1251C | Recombinant Chicken SNTB1 | Mammalian Cells | Chicken | His |
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| SNTB1-15703M | Recombinant Mouse SNTB1 Protein | Mammalian Cells | Mouse | His |
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| SNTB1-396Z | Recombinant Zebrafish SNTB1 | Mammalian Cells | Zebrafish | His |
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| Sntb1-8119M | Recombinant Mouse Sntb1 protein, His & T7-tagged | E.coli | Mouse | His&T7 | Ala2~Gly297 |
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| SNTB1-2248H | Recombinant Human SNTB1 Protein, MYC/DDK-tagged | HEK293 | Human | Myc&DDK |
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| Sntb1-6012M | Recombinant Mouse Sntb1 Protein, Myc/DDK-tagged | HEK293 | Mouse | Myc&DDK |
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| SNTB1-6027H | Recombinant Human SNTB1 Protein, Myc/DDK-tagged, C13 and N15-labeled | HEK293 | Human | Myc&DDK |
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| SNTB1-8543M | Recombinant Mouse SNTB1 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| SNTB1-8543M-B | Recombinant Mouse SNTB1 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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Involved Pathway
SNTB1 involved in several pathways and played different roles in them. We selected most pathways SNTB1 participated on our site, such as XPodNet - protein-protein interactions in the podocyte expanded by STRING, which may be useful for your reference. Also, other proteins which involved in the same pathway with SNTB1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| XPodNet - protein-protein interactions in the podocyte expanded by STRING | TENC1,CMIP,FLII,SDK1,CARF,SMARCD3,GAB3,GJB6,KCP,ARHGAP33 |
Protein Function
SNTB1 has several biochemical functions, for example, PDZ domain binding,actin binding,calmodulin binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SNTB1 itself. We selected most functions SNTB1 had, and list some proteins which have the same functions with SNTB1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| PDZ domain binding | DLG3,DTNA,PROSAPIP1,KIF14,PLEKHA2,DLG4,EXOC4,LRP2,PTENA,ATP2B4 |
| calmodulin binding | EPB41B,TRPC2,MYLK,MYH13,MAPKAPK2A,DCX,ATP2B1,MYH7,KCNQ1,EPB41 |
| structural molecule activity | BVES,SPRR2F,KRT7,LCE3D,KRTAP3-3,SPRR1A,KRT3,CLDN17,KLHL3,CLDN11A |
| actin binding | PFN1,WASLB,KLHL33,PARVA,SYNE1,MYH15,MYH7B,PTK2,RUSC1,EPS8L2 |
| protein binding | LYRM2,FAIM,AMY1B,SEPT10,ELP3,TDG,GLRX3,RIPPLY2,MLF1,KIF18B |
Interacting Protein
SNTB1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SNTB1 here. Most of them are supplied by our site. Hope this information will be useful for your research of SNTB1.
Scn7a;Dtna;Dmd;Ywhae;q8c7r5_mouse
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References
- Chung, SA; Brown, EE; et al. Lupus Nephritis Susceptibility Loci in Women with Systemic Lupus Erythematosus. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY 25:2859-2870(2014).
- Ishitobi, Y; Inoue, A; et al. Association of Microcephalin 1, Syntrophin-Beta 1, and Other Genes with Automatic Thoughts in the Japanese Population. AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS 165:492-501(2014).
