SNRPB
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Official Full Name
Small Nuclear Ribonucleoprotein Polypeptides B and B1 -
Overview
Small nuclear ribonucleoprotein-associated protein B and B' is a protein that in humans is encoded by the SNRPB gene. The protein encoded by this gene is one of several nuclear proteins that are found in common among U1, U2, U4/U6, and U5 small ribonucleoprotein particles (snRNPs). These snRNPs are involved in pre-mRNA splicing, and the encoded protein may also play a role in pre-mRNA splicing or snRNP structure. Autoantibodies from patients with systemic lupus erythematosus frequently recognize epitopes on the encoded protein. Two transcript variants encoding different isoforms (B and B') have been found for this gene. -
Synonyms
SNRPB;small nuclear ribonucleoprotein polypeptides B and B1;Sm protein B/B';COD;B polypeptide of Sm protein;Sm-B/B';sm-B/Sm-B';snRNP-B;small nuclear ribonucleoprotein polypeptide B;SmB/SmB';small nuclear ribonucleoprotein polypeptides B and B';small nuclear ribonucleoprotein-associated proteins B and B';SmB/B';SNRPB1;OTTHUMP00000030012;OTTHUMP00000030013
Recombinant Proteins
- Zebrafish
- Rhesus macaque
- Chicken
- Human
- Mouse
- Mammalian Cell
- HEK293
- Mammalian cells
- HEK293T
- His
- Non
- Myc&DDK
- Flag
- His&Fc&Avi
Involved Pathway
SNRPB involved in several pathways and played different roles in them. We selected most pathways SNRPB participated on our site, such as Spliceosome,Systemic lupus erythematosus, which may be useful for your reference. Also, other proteins which involved in the same pathway with SNRPB were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Spliceosome | SRSF5B,SRSF5,HSC70,HNRNPU,SRSF1,SNRNP200,PUF60,NHP2L1,LSM8,NCBP2 |
| Systemic lupus erythematosus | HIST1H2BE,HIST1H3C,SNRPD3,HIST1H2AI,HIST1H4M,HLA-DRA,HIST1H4I,FCGR3A,HIST1H2AE,Hc |
Protein Function
SNRPB has several biochemical functions, for example, histone pre-mRNA DCP binding,poly(A) RNA binding,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SNRPB itself. We selected most functions SNRPB had, and list some proteins which have the same functions with SNRPB. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | PDCD1,CHCHD3,WWP1,CPNE7,DZIP1L,MAGEA6,FHIT,NAA35,MPP5,ZAP70 |
| poly(A) RNA binding | ZCCHC6,RPL32,NOL7,PPRC1,SYF2,TNPO1,ANKRD17,EIF3G,SBDS,ZFP106 |
| histone pre-mRNA DCP binding | SLBP,LSM10,SNRPD3 |
Interacting Protein
SNRPB has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SNRPB here. Most of them are supplied by our site. Hope this information will be useful for your research of SNRPB.
CD2BP2;GEMIN4;CLNS1A;SNRPD3;SMN1
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