SMN2
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Official Full Name
sgp-130 -
Synonyms
sgp-130
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| SMN2-1659HCL | Recombinant Human SMN2 293 Cell Lysate | HEK293 | Human | Non |
|
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| SMN2-151H | Recombinant Human SMN2 Protein, DYKDDDDK-tagged | Human Cells | Human | Flag |
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Involved Pathway
SMN2 involved in several pathways and played different roles in them. We selected most pathways SMN2 participated on our site, such as RNA transport, which may be useful for your reference. Also, other proteins which involved in the same pathway with SMN2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| RNA transport | RPP25,TACC3,SUMO1,GEMIN7,DDX39B,AAAS,GEMIN4,RANGAP1A,RAE1,UBE2IA |
Protein Function
SMN2 has several biochemical functions, for example, RNA binding,identical protein binding,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SMN2 itself. We selected most functions SMN2 had, and list some proteins which have the same functions with SMN2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| RNA binding | EIF2C3,RBM4B,TRIM71,RBMY1B,APOBEC3F,THUMPD2,CPEB1B,SPI1,RNMTL1A,ZBP1 |
| protein binding | ULK2,ACVR1B,TRIM63,HNRPLL,RAB4B,NPBWR1,DPEP1,MUL1,DRG1,CAMK1 |
| identical protein binding | AXIN1,SDK2,CLDN11,FUS,AGXT2,SCHIP1,DNM1,IK,MRAP2,PLDN |
Interacting Protein
SMN2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SMN2 here. Most of them are supplied by our site. Hope this information will be useful for your research of SMN2.
GEMIN2
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References
- Mulcahy, PJ; Iremonger, K; et al. Gene Therapy: A Promising Approach to Treating Spinal Muscular Atrophy. HUMAN GENE THERAPY 25:575-586(2014).
- Mattis, VB; Butchbach, MER; et al. Detection of human survival motor neuron (SMN) protein in mice containing the SMN2 transgene: Applicability to preclinical therapy development for spinal muscular atrophy. JOURNAL OF NEUROSCIENCE METHODS 175:36-43(2008).
