SMG5
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Official Full Name
SMG5 nonsense mediated mRNA decay factor -
Overview
SMG5 is involved in nonsense-mediated mRNA decay (Ohnishi et al., 2003 [PubMed 14636577]).[supplied by OMIM, Mar 2008] -
Synonyms
SMG5;SMG5 nonsense mediated mRNA decay factor;EST1B;SMG-5;LPTSRP1;LPTS-RP1;protein SMG5;hSMG-5;RP11-54H19.7;EST1-like protein B;Est1p-like protein B;LPTS interacting protein;LPTS-interacting protein;ever shorter telomeres 1B;EST1 telomerase component homolog B;smg-5 homolog, nonsense mediated mRNA decay factor
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| SMG5-3066Z | Recombinant Zebrafish SMG5 | Mammalian Cell | Zebrafish | His |
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| SMG5-4344R | Recombinant Rhesus monkey SMG5 Protein, His-tagged | Mammalian Cell | Rhesus macaque | His |
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| SMG5-1650HCL | Recombinant Human SMG5 cell lysate | Human | Non |
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| SMG5-4160R | Recombinant Rhesus Macaque SMG5 Protein, His (Fc)-Avi-tagged | HEK293 | Rhesus macaque | His&Fc&Avi |
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| SMG5-4160R-B | Recombinant Rhesus Macaque SMG5 Protein Pre-coupled Magnetic Beads | HEK293 | Rhesus macaque |
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Involved Pathway
SMG5 involved in several pathways and played different roles in them. We selected most pathways SMG5 participated on our site, such as mRNA surveillance pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with SMG5 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| mRNA surveillance pathway | PPP1CAB,UPF3B,PPP1CAA,PPP2R5EB,EIF4A3,PPP2R5B,FIP1L1B,PPP2R2BB,PABPC1B,CPSF5 |
Protein Function
SMG5 has several biochemical functions, for example, protein binding,protein phosphatase 2A binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SMG5 itself. We selected most functions SMG5 had, and list some proteins which have the same functions with SMG5. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | IFT88,ROR2,AKAP7,SNX20,CUL4B,PTK6,KRT20,RXRG,NEU4,GSPT2 |
| protein phosphatase 2A binding | ENSAA,MAPT,STRN,RPS6KB1,FOXO1,BCL2,GRIN3A,PPP2R2A,PPME1,TRP53 |
Interacting Protein
SMG5 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SMG5 here. Most of them are supplied by our site. Hope this information will be useful for your research of SMG5.
SMG7;UPF1;TERT;TP53;UPF1;UPF3B;UPF3A;UPF3A
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References
- Geissler, V; Altmeyer, S; et al. The RNA helicase Ddx5/p68 binds to hUpf3 and enhances NMD of Ddx17/p72 and Smg5 mRNA. NUCLEIC ACIDS RESEARCH 41:7875-7888(2013).
