SMC4

  • Official Full Name

    structural maintenance of chromosomes 4

  • Overview

    Structural maintenance of chromosomes 2 (SMC2) and 4 (SMC4) proteins are subunits of the condensin complex, which enables chromosome condensation and maintains the compaction of chromosomes as they separate to opposite poles during anaphase (1-3). In addi

  • Synonyms

    SMC4;structural maintenance of chromosomes 4;SMC4 (structural maintenance of chromosomes 4, yeast) like 1 , SMC4 structural maintenance of chromosomes 4 like 1 (yeast) , SMC4L1;structural maintenance of chromosomes protein 4;CAP C;hCAP C;SMC protein 4;XCAP-C homolog;chromosome-associated polypeptide C;SMC4 structural maintenance of chromosomes 4-like 1;CAPC;CAP-C;SMC-4;SMC4L1;hCAP-C

Recombinant Proteins

  • Human
  • Mouse
  • Rhesus macaque
  • Chicken
  • Zebrafish
  • E.coli
  • Mammalian Cell
  • HEK293
  • GST
  • His
  • Non
  • His&Fc&Avi
Cat.# Product name Source (Host) Species Tag Protein Length Price
SMC4-2811H Recombinant Human SMC4, GST-tagged E.coli Human GST 143-439 a.a.
SMC4-15612M Recombinant Mouse SMC4 Protein Mammalian Cell Mouse His
SMC4-4340R Recombinant Rhesus monkey SMC4 Protein, His-tagged Mammalian Cell Rhesus macaque His
SMC4-6087C Recombinant Chicken SMC4 Mammalian Cell Chicken His
SMC4-9527Z Recombinant Zebrafish SMC4 Mammalian Cell Zebrafish His
SMC4-1649HCL Recombinant Human SMC4 cell lysate Human Non
SMC4-4156R Recombinant Rhesus Macaque SMC4 Protein, His (Fc)-Avi-tagged HEK293 Rhesus macaque His&Fc&Avi
SMC4-4156R-B Recombinant Rhesus Macaque SMC4 Protein Pre-coupled Magnetic Beads HEK293 Rhesus macaque
SMC4-8470M Recombinant Mouse SMC4 Protein, His (Fc)-Avi-tagged HEK293 Mouse His&Fc&Avi
SMC4-8470M-B Recombinant Mouse SMC4 Protein Pre-coupled Magnetic Beads HEK293 Mouse

    Involved Pathway

    SMC4 involved in several pathways and played different roles in them. We selected most pathways SMC4 participated on our site, such as Aurora B signaling,Cell Cycle,Cell Cycle, Mitotic, which may be useful for your reference. Also, other proteins which involved in the same pathway with SMC4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Condensation of Prophase Chromosomes SET,H3F3B.1,PHF8,MCPH1,NCAPH2,SETB,NCAPD3,SETA,SMC2,NCAPG2
    Mitotic Prophase ARPP19,SET,NEK6,NEK9,SETA,SMC2,ENSAB,NEK7,ENSAA,PHF8
    Condensation of Prometaphase Chromosomes SMC2,CSNK2A1,NCAPH,NCAPD2,CSNK2B,NCAPG,CSNK2A2
    M Phase CENPN,NDEL1,AHCTF1,CCDC99,CDCA5,ENSA,TMPO,APITD1,INCENP,DULLARD
    Mitotic Prometaphase CDCA5,CENPP,SPDL1,RANGAP1B,AHCTF1,NSL1,SGOL2,DSN1,ERCC6L,NDEL1B
    Cell Cycle, Mitotic MAU2,GINS4,SSNA1,GINS3,KIF2A,SMC2,ERCC6L,TMPO,WAPAL,AURKB
    Cell cycle SETB,CCNE1,MAPRE1A,CSNK2A1,CETN2,OFD1,NPM1,WRAP53,MCM3L,TGFB2
    Aurora B signaling KIF2C,PEBP1,INCENP,AURKC,KIF20A,NDC80,NPM1,RACGAP1,AURKB,NCAPD2

    Protein Function

    SMC4 has several biochemical functions, for example, ATP binding,protein binding,protein heterodimerization activity. Some of the functions are cooperated with other proteins, some of the functions could acted by SMC4 itself. We selected most functions SMC4 had, and list some proteins which have the same functions with SMC4. You can find most of the proteins on our site.

    Function Related Protein
    protein heterodimerization activity HIST3H2BB,HNF1B,TLR2,ABCG8,CREB3L3,MICU1,HIST1H2AA,UGT1A1,GCLC,GRIN2A
    protein binding KCNQ4,FKBP5,PDE6D,FTH1,MLST8,SPTLC1,FRMPD4,SEMA4D,CEP104,VPS53
    ATP binding RFK,DDX5,GATB,DDX56,NLRP4E,TTLL5,NMNAT1,RFC2,AKT3A,PFKFB2

    Interacting Protein

    SMC4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SMC4 here. Most of them are supplied by our site. Hope this information will be useful for your research of SMC4.

    MYC;SMC2;NCAPH;MCC;CASP4;IKBKE;NCAPH2;SMYD2;PHLDA3;IKBKG;hmuT;tgt;metE;mtlR;hemH2

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