SMC2
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Official Full Name
structural maintenance of chromosomes 2 -
Overview
Structural maintenance of chromosomes 2 (SMC2) and 4 (SMC4) proteins are subunits of the condensin complex, which enables chromosome condensation and maintains the compaction of chromosomes as they separate to opposite poles during anaphase (1-3). In addi -
Synonyms
SMC2;structural maintenance of chromosomes 2;SMC2 (structural maintenance of chromosomes 2, yeast) like 1 , SMC2 structural maintenance of chromosomes 2 like 1 (yeast) , SMC2L1;structural maintenance of chromosomes protein 2;CAP E;hCAP E;SMC-2;SMC
Recombinant Proteins
- Human
- Mouse
- Chicken
- Zebrafish
- E.coli
- Mammalian Cell
- E. coli
- HEK293
- Non
- His
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| SMC2-02H | Recombinant Human SMC2 Protein, Biotinylated-tagged | E.coli | Human | Non | ||
| SMC2-15610M | Recombinant Mouse SMC2 Protein | Mammalian Cell | Mouse | His |
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| SMC2-6783C | Recombinant Chicken SMC2 | Mammalian Cell | Chicken | His |
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| SMC2-9947Z | Recombinant Zebrafish SMC2 | Mammalian Cell | Zebrafish | His |
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| SMC2-055H | Recombinant Human structural maintenance of chromosomes 2 Protein, His tagged | E. coli | Human | His | 476-707aa |
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| SMC2-8469M | Recombinant Mouse SMC2 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| SMC2-8469M-B | Recombinant Mouse SMC2 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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Involved Pathway
SMC2 involved in several pathways and played different roles in them. We selected most pathways SMC2 participated on our site, such as Cell Cycle,Cell Cycle, Mitotic,Condensation of Prometaphase Chromosomes, which may be useful for your reference. Also, other proteins which involved in the same pathway with SMC2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| M Phase | RANGAP1B,NDEL1B,APITD1,CENPC1,GORASP1,NDEL1,VRK1,AHCTF1,CENPE,ITGB3BP |
| Cell Cycle, Mitotic | PDS5B,H3F3B.1,DYRK1A,PMF1,ZW10,ERCC6L,DNA2,GINS4,MLF1IP,ARPP19 |
| Cell cycle | SPC24,TFDP1A,TEX12,ENSAB,NCAPH2,EP300,STIL,MND1,DHFR,PDS5B |
| Mitotic Prometaphase | CCDC99,CENPQ,NDEL1A,DSN1,CDCA5,SGOL2,SKA2,NDC80,CENPI,SPC24 |
| Condensation of Prometaphase Chromosomes | SMC4,CSNK2B,NCAPG,CSNK2A1,NCAPD2,CSNK2A2,NCAPH |
| Mitotic Prophase | MASTL,ARPP19A,CTDNEP1B,SMC4,ENSAB,ARPP19,TMEM188,NEK7,NCAPG2,CTDNEP1A |
| Condensation of Prophase Chromosomes | H3F3B.1,PHF8,SET,H3F3D,SETA,NCAPD3,SETB,NCAPG2,NCAPH2,SMC4 |
Protein Function
SMC2 has several biochemical functions, for example, ATP binding,nucleotide binding,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SMC2 itself. We selected most functions SMC2 had, and list some proteins which have the same functions with SMC2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein heterodimerization activity | CHRAC1,TCF3A,TFAP2E,EGFR,HIST1H2AF,DDIT3,CHRNB2,JAM3,SLC51B,P2RY1 |
| protein binding | TRMT1,PEX3,LRP5,IFIT2,BAD,TMEM27,JOSD1,MAK,BANP,MTAP1A |
| nucleotide binding | KIF15,RBM28,RBM39B,PIF1,SMC5,NLRP9B,MYHZ1.2,SRSF5B,TNRC6B,GRK7A |
| ATP binding | DYNC1LI2,MAP2K2A,MYO9B,ATP13A1,PAPSS2,RENBP,ACTA2,NLRP4C,RIPK1,HSPA9 |
Interacting Protein
SMC2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SMC2 here. Most of them are supplied by our site. Hope this information will be useful for your research of SMC2.
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