SMC1A

  • Official Full Name

    structural maintenance of chromosomes 1A

  • Overview

    Structural maintenance of chromosomes 1 (SMC1) protein is a chromosomal protein member of the cohesin complex that enables sister chromatid cohesion and plays a role in DNA repair. ATM/NBS1-dependent phosphorylation of SMC1 occurs at Ser957 and Ser966 in

  • Synonyms

    SMC1A;structural maintenance of chromosomes 1A;SMC1 (structural maintenance of chromosomes 1, yeast) like 1 , SMC1 structural maintenance of chromosomes 1 like 1 (yeast) , SMC1L1;structural maintenance of chromosomes protein 1A;DXS423E;KIAA0178;SB1

Recombinant Proteins

  • Human
  • Mouse
  • Rat
  • Chicken
  • Zebrafish
  • E.coli
  • Mammalian Cell
  • HEK293
  • GST
  • His
  • Non
  • His&Fc&Avi
Cat.# Product name Source (Host) Species Tag Protein Length Price
SMC1A-2808H Recombinant Human SMC1A, GST-tagged E.coli Human GST 685-1034aa
SMC1A-2907H Recombinant Human SMC1A protein, His-tagged E.coli Human His 685-1034 aa
SMC1A-15608M Recombinant Mouse SMC1A Protein Mammalian Cell Mouse His
SMC1A-5616R Recombinant Rat SMC1A Protein Mammalian Cell Rat His
SMC1A-6085C Recombinant Chicken SMC1A Mammalian Cell Chicken His
SMC1A-7517Z Recombinant Zebrafish SMC1A Mammalian Cell Zebrafish His
SMC1A-1666HCL Recombinant Human SMC1A 293 Cell Lysate HEK293 Human Non
SMC1A-5275R Recombinant Rat SMC1A Protein, His (Fc)-Avi-tagged HEK293 Rat His&Fc&Avi
SMC1A-5275R-B Recombinant Rat SMC1A Protein Pre-coupled Magnetic Beads HEK293 Rat
SMC1A-8468M Recombinant Mouse SMC1A Protein, His (Fc)-Avi-tagged HEK293 Mouse His&Fc&Avi
SMC1A-8468M-B Recombinant Mouse SMC1A Protein Pre-coupled Magnetic Beads HEK293 Mouse

    Involved Pathway

    SMC1A involved in several pathways and played different roles in them. We selected most pathways SMC1A participated on our site, such as Cell cycle,Oocyte meiosis, which may be useful for your reference. Also, other proteins which involved in the same pathway with SMC1A were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Cell cycle CEP135,CDC14AA,STIL,ITGB3BP,STAG2,CEP152,CCNB2,CENPN,CSNK2A2,TFDP2
    Oocyte meiosis YWHABB,YWHAG1,REC8,PPP2CB,PPP3R1B,PPP2R5EB,PPP3CA,REC8B,PPP1CAA,PRKACAB

    Protein Function

    SMC1A has several biochemical functions, for example, ATP binding,chromatin binding,mediator complex binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SMC1A itself. We selected most functions SMC1A had, and list some proteins which have the same functions with SMC1A. You can find most of the proteins on our site.

    Function Related Protein
    chromatin binding ORC1L,UBTFL,GATA1A,TBL1Y,GATA2,HDGFRP2,TGIF1,NCAPD3,GPR30,GATA2A
    protein binding CEP85,GOLGA2,UTP3,MAPRE2,AES,DHPS,RALBP1,KLF12,SIGLEC8,GTF3C4
    poly(A) RNA binding ARF1,C4BPA,RPS3A,NKRF,DHX35,NXF1,HNRNPH2,SKIV2L2,ZC3H14,RPL29
    mediator complex binding MED1,SMC3,NIPBL
    microtubule motor activity KIF7,APPBP2,KIF3B,KIF15,KIF9,DNAH11,DYNLRB2,KLC2,KIF2B,KIFC3
    protein heterodimerization activity H2AFX,UBXN6,BDKRB2,TOP2B,KCNA3,BCL11A,P4HB,SNX1,TENM3,TOP2A
    ATP binding MYLK3,MAPKAPK2,NUAK2,TTN,ERBB4,RPS6KA3B,EPHA2,SMARCAL1,BAZ1B,MYHC4

    Interacting Protein

    SMC1A has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SMC1A here. Most of them are supplied by our site. Hope this information will be useful for your research of SMC1A.

    SMC3;RAD21;WAPAL

    Resources

    Research Area

    Metaphase (Mitotic Spindle) Checkpoints

    References

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