SLIRP
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Official Full Name
SRA stem-loop interacting RNA binding protein -
Overview
Steroid receptor RNA activator (SRA, or SRA1; MIM 603819) is a complex RNA molecule containing multiple stable;stem-loop structures that functions in coactivation of nuclear receptors. SLIRP interacts with stem-loop structure-7;of SRA (STR7) and modulates nuclear receptor transactivation (Hatchell et al., 2006 (PubMed 16762838)). -
Synonyms
SLIRP;SRA stem-loop interacting RNA binding protein;C14orf156, chromosome 14 open reading frame 156;SRA stem-loop-interacting RNA-binding protein, mitochondrial;DC50;C14orf156;Chromosome 14 open reading frame 156;PD04872;SRA stem loop interacting RNA binding protein, mitochondrial
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
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| SLIRP-974H | Recombinant Human SLIRP | Mammalian Cell | Human | His |
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| SLIRP-8283HCL | Recombinant Human C14orf156 293 Cell Lysate | HEK293 | Human | Non |
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| SLIRP-4086H | Recombinant Human SLIRP Protein, His (Fc)-Avi-tagged | HEK293 | Human | His&Fc&Avi |
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| SLIRP-4086H-B | Recombinant Human SLIRP Protein Pre-coupled Magnetic Beads | HEK293 | Human |
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| Slirp-5943M | Recombinant Mouse Slirp Protein, Myc/DDK-tagged | HEK293T | Mouse | Myc&DDK |
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Involved Pathway
SLIRP involved in several pathways and played different roles in them. We selected most pathways SLIRP participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with SLIRP were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
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Protein Function
SLIRP has several biochemical functions, for example, nucleotide binding,poly(A) RNA binding,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SLIRP itself. We selected most functions SLIRP had, and list some proteins which have the same functions with SLIRP. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| poly(A) RNA binding | IGF2BP3,NCBP1,BZW1,RPL23A,SYNCRIP,HRSP12,ZNF326,TRMT1,RPS28,DHX35 |
| nucleotide binding | ATP1A3A,PPRC1,GTF2F2A,RAB1BA,ACTB2,GNAIA,MATR3,RBM33,ARL8BA,ATP2B1 |
| protein binding | PRKX,FAM32A,PTK2,CLOCK,KREMEN1,GRB2,SLC8A1,SMC2,GLI3,GFER |
Interacting Protein
SLIRP has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SLIRP here. Most of them are supplied by our site. Hope this information will be useful for your research of SLIRP.
CCDC102B;LRPPRC;MTUS2;KRT40;PNMA1;vpu;CSNK2A1
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References
- Colley, SM; Wintle, L; et al. Loss of the Nuclear Receptor Corepressor SLIRP Compromises Male Fertility. PLOS ONE 8:-(2013).
- Hatchell, EC; Colley, SM; et al. SLIRP, a small SRA binding protein, is a nuclear receptor corepressor. MOLECULAR CELL 22:657-668(2006).
