SLC9A8
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Official Full Name
solute carrier family 9 (sodium/hydrogen exchanger), member 8 -
Overview
Sodium-hydrogen exchangers (NHEs), such as SLC9A8, are integral transmembrane proteins that exchange extracellular Na+;for intracellular H+. NHEs have multiple functions, including intracellular pH homeostasis, cell volume regulation,;and electroneutral NaCl absorption in epithelia (Xu et al., 2008 (PubMed 18209477)). -
Synonyms
SLC9A8;solute carrier family 9 (sodium/hydrogen exchanger), member 8;solute carrier family 9 (sodium/hydrogen exchanger), isoform 8;sodium/hydrogen exchanger 8;KIAA0939;NHE8;Na(+)/H(+) exchanger 8;NHE 8;Sodium/ hydrogen exchanger 8;Solute carrier family 9 member 8;NHE-8
Recombinant Proteins
- Human
- Mouse
- Zebrafish
- Chicken
- Rat
- Cynomolgus
- E.coli
- Mammalian Cell
- HEK293
- GST
- His
- Non
- His&Fc&Avi
Involved Pathway
SLC9A8 involved in several pathways and played different roles in them. We selected most pathways SLC9A8 participated on our site, such as SLC-mediated transmembrane transport,Sodium/Proton exchangers,Transmembrane transport of small molecules, which may be useful for your reference. Also, other proteins which involved in the same pathway with SLC9A8 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| SLC-mediated transmembrane transport | SLC30A3,SLC30A2,SLC4A1B,SLC20A1B,SLC4A2A,SLC26A3.2,SLC2A13,SLC15A4,SLC2A13B,SLC15A1B |
| Transmembrane transport of small molecules | SLC6A19A,TRPM4A,SLC4A2A,TRPC4A,AQP9B,MMGT1,ASPH,SLC35B4,SLC9B2,CLCN6 |
| Sodium/Proton exchangers | SLC9A7,SLC9A9,SLC9A3.1,SLC9A3.2,SLC9A6A,SLC9A5,SLC9A6B |
| Transport of inorganic cations/anions and amino acids/oligopeptides | SLC15A2,SLC7A6,SLC26A3.2,SLC7A3A,SLC15A1B,SLC6A15,SLC20A1,SLC26A7,SLC12A1,SLC12A4 |
Protein Function
SLC9A8 has several biochemical functions, for example, potassium:proton antiporter activity,sodium:proton antiporter activity. Some of the functions are cooperated with other proteins, some of the functions could acted by SLC9A8 itself. We selected most functions SLC9A8 had, and list some proteins which have the same functions with SLC9A8. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| potassium:proton antiporter activity | SLC9A7 |
| sodium:proton antiporter activity | SLC9A4,SLC9A7,SLC9A3.1,SLC9A3,SLC9A6B,SLC9A9,SLC9A6A,SLC9A3.2,SLC9A5,SLC9A1 |
Interacting Protein
SLC9A8 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SLC9A8 here. Most of them are supplied by our site. Hope this information will be useful for your research of SLC9A8.
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