SLC5A4
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Official Full Name
solute carrier family 5 (glucose activated ion channel), member 4 -
Overview
SLC5A4 is a sodium dependent low affinity glucose cotransporter. -
Synonyms
SLC5A4;solute carrier family 5 (glucose activated ion channel), member 4;SAAT1;SGLT3;DJ90G24.4;low affinity sodium-glucose cotransporter;sodium transporter;Na(+)/glucose cotransporter 3;sodium/glucose cotransporter 3;solute carrier family 5 member 4;low affinity sodium glucose cotransporter;solute carrier family 5 (low affinity glucose cotransporter), member 4;solute carrier family 5 (neutral amino acid transporters, system A), member 4
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| SLC5A4-2777H | Recombinant Human SLC5A4, His-tagged | E.coli | Human | His | 579-633aa |
Involved Pathway
SLC5A4 involved in several pathways and played different roles in them. We selected most pathways SLC5A4 participated on our site, such as Hexose transport,Inositol transporters,Metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with SLC5A4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| SLC-mediated transmembrane transport | SLC35B3,SLC26A3.1,SLC24A6,SLC6A9,SLC36A2,SLC13A5A,SLC9A7,SLC15A3,SLC2A13B,SLC6A15 |
| Hexose transport | SLC2A3,SLC5A9,GCKR,SLC5A2 |
| Na+-dependent glucose transporters | SLC5A9,SLC5A2 |
| Metabolism | PRKRA,NDOR1,TIMMDC1,TYMP,NUBP2,PDK4,CIAPIN1,CYP2K18,SLC5A9,CYP2A13 |
| Transmembrane transport of small molecules | TSC22D3,ASPH,SLC28A2,CP,TRPC5A,LCN15,SLC9A10,SLC22A15,MMGT1,MYO5B |
| Inositol transporters | SLC5A3A,SLC2A13B,SLC5A9,SLC2A13,SLC5A11,SLC5A2 |
| Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds | SLC22A18,SLC31A1,SLC2A13B,SLC13A1,SLC39A8,SLC30A5,SLC13A4,SLC2A15A,SLC6A20,SLC6A20B |
| Metabolism of carbohydrates | DSEL,B3GAT2,SLC35B2,SLC25A13,PFKLB,SLC25A1A,SLC25A10,SLC5A2,GLB1L,KIAA1199 |
Protein Function
SLC5A4 has several biochemical functions, for example, symporter activity. Some of the functions are cooperated with other proteins, some of the functions could acted by SLC5A4 itself. We selected most functions SLC5A4 had, and list some proteins which have the same functions with SLC5A4. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| symporter activity | SLC1A2B,SLC10A7,SLC6A1A,SLC16A1,SLC16A12,SLC6A6B,SLC34A3,SLC1A8B,SLC6A6,SLC34A2 |
Interacting Protein
SLC5A4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SLC5A4 here. Most of them are supplied by our site. Hope this information will be useful for your research of SLC5A4.
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References
- Han, JY; Lee, YS; et al. Whole-genome analysis of a patient with early-stage small-cell lung cancer. PHARMACOGENOMICS JOURNAL 14:503-508(2014).
- Fowler, KE; Pong-Wong, R; et al. Genome wide analysis reveals single nucleotide polymorphisms associated with fatness and putative novel copy number variants in three pig breeds. BMC GENOMICS 14:-(2013).
- Kadam, RS; Ramamoorthy, P; et al. Hypoxia Alters Ocular Drug Transporter Expression and Activity in Rat and Calf Models: Implications for Drug Delivery. MOLECULAR PHARMACEUTICS 10:2350-2361(2013).
- Diez-Sampedro, A; Hirayama, BA; et al. A glucose sensor hiding in a family of transporters. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 100:11753-11758(2003).
