SLC5A2

  • Official Full Name

    solute carrier family 5 (sodium/glucose cotransporter), member 2

  • Overview

    This gene encodes a member of the sodium glucose cotransporter family which are sodium-dependent glucose transport;proteins. The encoded protein is the major cotransporter involved in glucose reabsorption in the kidney. Mutations in;this gene are associated with renal glucosuria.

  • Synonyms

    SLC5A2;solute carrier family 5 (sodium/glucose cotransporter), member 2;SGLT2;sodium/glucose cotransporter 2;Low affinity sodium glucose cotransporter;Low affinity sodium-glucose cotransporter;Na(+) glucose cotransporter 2;Na(+)/glucose cotransporter 2;OTTHUMP00000163298;SC5A2_HUMAN;SGLT 2;SLC5A 2;Sodium glucose cotransporter 2;Solute carrier family 5 (sodium glucose cotransporter) member 2;Solute carrier family 5 (sodium/glucose transporter), member 2;Solute carrier family 5 member 2

Recombinant Proteins

  • Zebrafish
  • Mouse
  • Human
  • Rat
  • Mammalian Cell
  • Wheat Germ
  • HEK293
  • E.coli
  • In vitro E. coli expression system
  • Mammalian cells
  • His
  • Non
  • His&Myc
  • His&Myc&SUMO
  • His&Fc&Avi
Cat.# Product name Source (Host) Species Tag Protein Length Price
SLC5A2-12179Z Recombinant Zebrafish SLC5A2 Mammalian Cell Zebrafish His
SLC5A2-15482M Recombinant Mouse SLC5A2 Protein Mammalian Cell Mouse His
SLC5A2-30972TH Recombinant Human SLC5A2 Wheat Germ Human Non 50 amino acids
SLC5A2-1709HCL Recombinant Human SLC5A2 293 Cell Lysate HEK293 Human Non
Slc5a2-2078R Recombinant Rat Slc5a2 Protein, His-tagged E.coli Rat His Thr546-Ala648
SLC5A2-2210H Recombinant Human SLC5A2 Protein (1-102 aa), His-Myc-tagged E.coli Human His&Myc 1-102 aa
SLC5A2-2396H Recombinant Human SLC5A2 Transmembrane protein, His-SUMO & Myc-tagged In vitro E. coli expression system Human His&Myc&SUMO 1-102aa
SLC5A2-6306H Recombinant Human SLC5A2 Protein (Ser335-Leu423), C-His tagged Mammalian cells Human His Ser335-Leu423
SLC5A2-8399M Recombinant Mouse SLC5A2 Protein, His (Fc)-Avi-tagged HEK293 Mouse His&Fc&Avi
SLC5A2-8399M-B Recombinant Mouse SLC5A2 Protein Pre-coupled Magnetic Beads HEK293 Mouse

    Involved Pathway

    SLC5A2 involved in several pathways and played different roles in them. We selected most pathways SLC5A2 participated on our site, such as Hexose transport,Inositol transporters,Metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with SLC5A2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Na+-dependent glucose transporters SLC5A9,SLC5A4
    Inositol transporters SLC5A3A,SLC5A11,SLC2A13,SLC5A9,SLC2A13B,SLC5A4
    Metabolism of carbohydrates B3GNT2,SLC25A12,CHST14,SLC25A10,FMODA,STAB2,SLC35D2,SLC35B3,SLC2A3,HPSE
    SLC-mediated transmembrane transport SLC6A15,SLC31A1,SLC4A2A,SLC7A3,SLC16A8,SLC22A15,RHCGL1,RHAG,SLC13A4,SLC10A6
    Hexose transport SLC5A4,GCKR,SLC2A3,SLC5A9
    Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds SLC2A6,SLC5A11,SLC30A5,RHCG2A,RHCGA,MATE4,SLC6A6A,SLC47A1,SLC6A7,SLC2A8
    Metabolism UCP3,CYP8B2,ADSL,NUDT4A,BRP44,LYVE1,CERS4A,TIAM2,CHAT,AS3MT
    Transmembrane transport of small molecules BEST4,ANO7,SLC29A2,SLC2A13,TRPC4A,SLC47A1,SLC20A1,TRPC4APB,PDZD11,SLC35A3A

    Protein Function

    SLC5A2 has several biochemical functions, for example, low-affinity glucose:sodium symporter activity. Some of the functions are cooperated with other proteins, some of the functions could acted by SLC5A2 itself. We selected most functions SLC5A2 had, and list some proteins which have the same functions with SLC5A2. You can find most of the proteins on our site.

    Function Related Protein

    Interacting Protein

    SLC5A2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SLC5A2 here. Most of them are supplied by our site. Hope this information will be useful for your research of SLC5A2.

    Resources

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