SLC39A5
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Official Full Name
solute carrier family 39 (metal ion transporter), member 5 -
Overview
Zinc is an essential cofactor for hundreds of enzymes. It is involved in protein, nucleic acid, carbohydrate, and lipid;metabolism, as well as in the control of gene transcription, growth, development, and differentiation. SLC39A5 belongs;to a subfamily of proteins that show structural characteristics of zinc transporters (Taylor and Nicholson, 2003;(PubMed 12659941)). -
Synonyms
SLC39A5;solute carrier family 39 (metal ion transporter), member 5;zinc transporter ZIP5;LZT Hs7;MGC34778;OTTHUMP00000211153;OTTHUMP00000211154;S39A5_HUMAN;Solute carrier family 39 member 5;Zinc transporter ZIP5 [Precursor];ZIP 5;ZIP-5;ZIP5;Zrtand Irt like protein 5;Zrt- and Irt-like protein 5;LZT-Hs7
Recombinant Proteins
- Human
- Mouse
- Mus musculus
- E.coli
- Mammalian Cell
- HEK293
- E.coli expression system
- HEK293T
- Wheat Germ
- In Vitro Cell Free System
- His
- Non
- Myc&DDK
- GST
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| SLC39A5-2765H | Recombinant Human SLC39A5, His-tagged | E.coli | Human | His | 23-215aa | |
| SLC39A5-15438M | Recombinant Mouse SLC39A5 Protein | Mammalian Cell | Mouse | His |
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| SLC39A5-1718HCL | Recombinant Human SLC39A5 293 Cell Lysate | HEK293 | Human | Non |
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| RFL15879HF | Recombinant Full Length Human Zinc Transporter Zip5(Slc39A5) Protein, His-Tagged | E.coli expression system | Human | His | Full L. Full Length (21-540) |
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| RFL19670MF | Recombinant Full Length Mouse Zinc Transporter Zip5(Slc39A5) Protein, His-Tagged | E.coli expression system | Mus musculus | His | Full L. Full Length of Mature Protein (20-535) |
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| Slc39a5-5931M | Recombinant Mouse Slc39a5 Protein, Myc/DDK-tagged | HEK293T | Mouse | Myc&DDK |
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| SLC39A5-659H | Recombinant Human SLC39A5 Protein, GST-tagged | Wheat Germ | Human | GST | 21-539 aa |
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| SLC39A5-6805HF | Recombinant Full Length Human SLC39A5 Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 21-539 amino acids |
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| SLC39A5-8367M | Recombinant Mouse SLC39A5 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| SLC39A5-8367M-B | Recombinant Mouse SLC39A5 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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Involved Pathway
SLC39A5 involved in several pathways and played different roles in them. We selected most pathways SLC39A5 participated on our site, such as Metal ion SLC transporters,SLC-mediated transmembrane transport,Transmembrane transport of small molecules, which may be useful for your reference. Also, other proteins which involved in the same pathway with SLC39A5 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Zinc transporters | SLC39A10,SLC39A2,SLC39A7,SLC39A3,SLC30A1A,SLC30A1B,SLC39A8,SLC39A1,SLC39A14,SLC39A6 |
| Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds | SLC5A4,SLC13A5A,SLC30A8,SLC13A4,SLC6A5,SLC2A10,SLC13A5,SLC22A15,SLC30A6,RHCGA |
| Transmembrane transport of small molecules | ATP2B1B,SLC2A10,MATE4,ABCD3B,SRI,CLCA1,SLC47A1,CLCN1,SLC22A12,TSC22D3 |
| SLC-mediated transmembrane transport | SLC5A2,SLC28A1,SLC6A9,SLC13A3,SLC3A2A,LCN12,SLC28A3,RHCG,SLC4A4A,SLC1A2A |
| Metal ion SLC transporters | SLC30A3,SLC30A1B,SLC39A10,SLC31A1,SLC39A8,SLC39A3,SLC30A6,SLC30A8,SLC39A7,SLC39A14 |
| Zinc influx into cells by the SLC39 gene family | SLC39A6,SLC39A8,SLC39A14,SLC39A7,SLC39A10,SLC39A2,SLC39A3,SLC39A1 |
Protein Function
SLC39A5 has several biochemical functions, for example, metal ion transmembrane transporter activity,molecular_function. Some of the functions are cooperated with other proteins, some of the functions could acted by SLC39A5 itself. We selected most functions SLC39A5 had, and list some proteins which have the same functions with SLC39A5. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| metal ion transmembrane transporter activity | SLC39A6,SLC39A9,SLC39A14,SLC39A8 |
| molecular_function | MXRA8,REEP6,CCDC6A,STAMBPB,MARCH9,MOB3A,FAM194A,CENPV,TMEM14A,SDK1 |
Interacting Protein
SLC39A5 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SLC39A5 here. Most of them are supplied by our site. Hope this information will be useful for your research of SLC39A5.
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References
- He, L; Girijashanker, K; et al. ZIP8, member of the solute-carrier-39 (SLC39) metal-transporter family: Characterization of transporter properties. MOLECULAR PHARMACOLOGY 70:171-180(2006).
