SLC38A3
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Official Full Name
solute carrier family 38, member 3 -
Overview
Sodium-coupled neutral amino acid transporter 3 is a protein that in humans is encoded by the SLC38A3 gene. -
Synonyms
SLC38A3;solute carrier family 38, member 3;sodium-coupled neutral amino acid transporter 3;G17;SN1;N system amino acid transporter 1;NAT1;SNAT3;Sodium coupled neutral amino acid transporter 3;Solute carrier family 38 member 3;System N1 Na+ and H+ coupled glutamine transporter;N-system amino acid transporter 1;system N amino acid transporter 1;Na(+)-coupled neutral amino acid transporter 3;system N1 Na+ and H+-coupled glutamine transporter
Recombinant Proteins
- Human
- Mouse
- Rhesus macaque
- Rat
- E.coli
- Mammalian Cell
- HEK293
- His
- Non
- His&Fc&Avi
Involved Pathway
SLC38A3 involved in several pathways and played different roles in them. We selected most pathways SLC38A3 participated on our site, such as Amino acid transport across the plasma membrane,GABAergic synapse,Glutamatergic synapse, which may be useful for your reference. Also, other proteins which involved in the same pathway with SLC38A3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Transmembrane transport of small molecules | SLC13A5,AQP10,SLC1A2A,SCNN1D,MIPA,ATP1A1A.5,SLC29A4,SLC34A2A,ATP7B,SLC47A1 |
| SLC-mediated transmembrane transport | LCN15,SLC39A1,SLC1A3B,RHBG,SLC9A3.1,SLC30A3,SLC7A6,SLC20A1,SLC3A2B,SLC15A1B |
| Proximal tubule bicarbonate reclamation | SLC25A10,ATP1B1,PCK1,AQP1,SLC9A3,Car2,CA2,GLS2,ATP1B3,FXYD2 |
| Glutamatergic synapse | GRIK2,SLC17A8,SLC1A3,SHANK2,ITPR1,PLA2G4D,GRIN3B,GNG2,MAPK3,PLA2G4A |
| Transport of inorganic cations/anions and amino acids/oligopeptides | SLC6A20B,SLC9A6B,SLC17A1,SLC3A2A,SLC43A2,SLC9A5,SLC6A6,SLC6A6A,SLC15A3,SLC7A10 |
| Amino acid transport across the plasma membrane | SLC3A2A,SLC6A20A,SLC43A1A,SLC6A18,SLC3A2B,SLC43A2A,SLC1A4,SLC6A12,SLC6A6,SLC6A20 |
| GABAergic synapse | GAD1,GNG5,SLC38A2,HAP1,GABRA3,GABARAPL2,GLS,GABRB3,GAD2,Adcy4 |
Protein Function
SLC38A3 has several biochemical functions, for example, L-alanine transmembrane transporter activity,L-asparagine transmembrane transporter activity,L-glutamine transmembrane transporter activity. Some of the functions are cooperated with other proteins, some of the functions could acted by SLC38A3 itself. We selected most functions SLC38A3 had, and list some proteins which have the same functions with SLC38A3. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| L-alanine transmembrane transporter activity | SLC36A3,SLC36A4,SLC36A1,SLC1A4,SLC36A2,SLC38A7 |
| L-asparagine transmembrane transporter activity | SLC38A7 |
| L-glutamine transmembrane transporter activity | SLC1A5,SLC38A7,SLC1A4,SLC38A1 |
| L-histidine transmembrane transporter activity | SLC38A7,SLC15A4 |
| symporter activity | SLC6A6B,SLC1A2B,SLC6A2,SLC6A1B,SLC17A4,SLC38A1,SLC16A7,SLC17A1,SLC15A3,SLC1A2A |
| antiporter activity | SLC7A13,SLC7A3,SLC35C2,SLC7A8,SLC35E4,SLC7A1,SLC7A7,SLC7A5,SLC4A8,SLC35E1 |
Interacting Protein
SLC38A3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SLC38A3 here. Most of them are supplied by our site. Hope this information will be useful for your research of SLC38A3.
HMGN1;COL6A2;SETDB1
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References
- Hagglund, MGA; Sreedharan, S; et al. Identification of SLC38A7 (SNAT7) Protein as a Glutamine Transporter Expressed in Neurons. JOURNAL OF BIOLOGICAL CHEMISTRY 286:20500-20511(2011).
