SLC37A4
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Official Full Name
solute carrier family 37 (glucose-6-phosphate transporter), member 4 -
Overview
This gene regulates glucose-6-phosphate transport from the cytoplasm to the lumen of the endoplasmic reticulum, in order to maintain glucose homeostasis. It also plays a role in ATP-mediated calcium sequestration in the lumen of the endoplasmic reticulum. Mutations in this gene have been associated with various forms of glycogen storage disease. Alternative splicing in this gene results in multiple transcript variants. -
Synonyms
SLC37A4;solute carrier family 37 (glucose-6-phosphate transporter), member 4;G6PT1, G6PT2, G6PT3, glucose 6 phosphatase, transport (glucose 6 phosphate) protein 1;glucose-6-phosphate translocase;GSD1b;GSD1c;GSD1d;G6PT2;MGC15729;PRO0685;TRG19;G6PT1;G6PT1_HUMAN;G6PT3;Glucose-5-phosphate transporter;Glucose-6-phosphatase, transport (glucose) protein 3;Glucose-6-phosphatase, transport (glucose-6-phosphate) protein 1;Glucose-6-phosphatase, transport (phosphate/pyrophosphate) protein 2;Glucose-6-phosphate transporter 1;Microsomal glucose-6-phosphate transporter;Solute carrier family 37 member 4;Transformation-related gene 19 protein;TRG-19
Recombinant Proteins
- Human
- Rhesus macaque
- E.coli
- Wheat Germ
- Mammalian Cell
- HEK293
- Baculovirus-Insect cells
- Insect Cell
- Yeast
- GST
- Non
- His
- His&Flag&MBP
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| SLC37A4-2758H | Recombinant Human SLC37A4, GST-tagged | E.coli | Human | GST | 1-93aa | |
| SLC37A4-31417TH | Recombinant Human SLC37A4 | Wheat Germ | Human | Non | 49 amino acids |
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| SLC37A4-4282R | Recombinant Rhesus monkey SLC37A4 Protein, His-tagged | Mammalian Cell | Rhesus macaque | His |
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| SLC37A4-1726HCL | Recombinant Human SLC37A4 293 Cell Lysate | HEK293 | Human | Non |
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| SLC37A4-0416H | Recombinant Human SLC37A4 Protein (Met1-Cys176), C-His-tagged | Baculovirus-Insect cells | Human | His | Met1-Cys176 |
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| SLC37A4-0569H | Recombinant Human SLC37A4 Protein (A2-E429), 8×His-MBP, Flag tagged | Insect Cell | Human | His&Flag&MBP | A2-E429 |
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| SLC37A4-4098R | Recombinant Rhesus Macaque SLC37A4 Protein, His (Fc)-Avi-tagged | HEK293 | Rhesus macaque | His&Fc&Avi |
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| SLC37A4-4098R-B | Recombinant Rhesus Macaque SLC37A4 Protein Pre-coupled Magnetic Beads | HEK293 | Rhesus macaque |
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| SLC37A4-5789H | Recombinant Human SLC37A4 Protein (Met1-Cys176), C-His tagged | Yeast | Human | His | Met1-Cys176 |
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Involved Pathway
SLC37A4 involved in several pathways and played different roles in them. We selected most pathways SLC37A4 participated on our site, such as Carbohydrate digestion and absorption, which may be useful for your reference. Also, other proteins which involved in the same pathway with SLC37A4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Carbohydrate digestion and absorption | ATP1A2,G6PC3,ATP1A3,ATP1B3,PIK3R1,HKDC1,PIK3R3,TAS1R3,HK1,ATP1A1 |
Protein Function
SLC37A4 has several biochemical functions, for example, glucose-6-phosphate transmembrane transporter activity,transporter activity. Some of the functions are cooperated with other proteins, some of the functions could acted by SLC37A4 itself. We selected most functions SLC37A4 had, and list some proteins which have the same functions with SLC37A4. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| transporter activity | SLC22A23,RASSF9,AP3B2,SLCO3A1,XPO1,ATP5O,CRABP2A,TMEM184BA,AP1B1,APODB |
| glucose-6-phosphate transmembrane transporter activity | SLC37A4A,SLC37A4B |
Interacting Protein
SLC37A4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SLC37A4 here. Most of them are supplied by our site. Hope this information will be useful for your research of SLC37A4.
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References
- Franca, MR; Mesquita, FS; et al. Modulation of periovulatory endocrine profiles in beef cows: consequences for endometrial glucose transporters and uterine fluid glucose levels. DOMESTIC ANIMAL ENDOCRINOLOGY 50:83-90(2015).
- Melis, D; Della Casa, R; et al. Involvement of endocrine system in a patient affected by Glycogen storage disease 1b: speculation on the role of autoimmunity. ITALIAN JOURNAL OF PEDIATRICS 40:-(2014).
