SLC36A2

  • Official Full Name

    solute carrier family 36 (proton/amino acid symporter), member 2
  • Overview

    This gene encodes a pH-dependent proton-coupled amino acid transporter that belongs to the amino acid auxin permease 1 protein family. The encoded protein primarily transports small amino acids such as glycine, alanine and proline. Mutations in this gene are associated with iminoglycinuria and hyperglycinuria.
  • Synonyms

    SLC36A2;solute carrier family 36 (proton/amino acid symporter), member 2;proton-coupled amino acid transporter 2;PAT2;TRAMD1;tramdorin;MGC119660;A530067G19Rik;FLJ16051;MGC119658;Proton coupled amino acid transporter 2;Proton/amino acid transporter 2;Solute carrier family 36 (proton/amino acid symporter) member 2;Solute carrier family 36 member 2;Tramdorin 1;tramdorin-1;OTTHUMP00000160624;OTTHUMP00000224111

Recombinant Proteins

  • Human
  • Mouse
  • Rat
  • E.coli
  • Mammalian Cell
  • HEK293
  • His
  • His&Fc&Avi
Cat.# Product name Source (Host) Species Tag Protein Length Price
SLC36A2-2755H Recombinant Human SLC36A2, His-tagged E.coli Human His 1-70aa
SLC36A2-15412M Recombinant Mouse SLC36A2 Protein Mammalian Cell Mouse His
SLC36A2-5521R Recombinant Rat SLC36A2 Protein Mammalian Cell Rat His
SLC36A2-5180R Recombinant Rat SLC36A2 Protein, His (Fc)-Avi-tagged HEK293 Rat His&Fc&Avi
SLC36A2-5180R-B Recombinant Rat SLC36A2 Protein Pre-coupled Magnetic Beads HEK293 Rat
SLC36A2-8346M Recombinant Mouse SLC36A2 Protein, His (Fc)-Avi-tagged HEK293 Mouse His&Fc&Avi
SLC36A2-8346M-B Recombinant Mouse SLC36A2 Protein Pre-coupled Magnetic Beads HEK293 Mouse

    Involved Pathway

    SLC36A2 involved in several pathways and played different roles in them. We selected most pathways SLC36A2 participated on our site, such as Amino acid transport across the plasma membrane,Proton-coupled neutral amino acid transporters,SLC-mediated transmembrane transport, which may be useful for your reference. Also, other proteins which involved in the same pathway with SLC36A2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Transmembrane transport of small molecules SLC9A10,SLC29A3,SLC35A1,SLC7A3,ANKHB,SLC20A1A,SLC16A7,SLC6A20A,SLC44A5B,SLC5A4
    Amino acid transport across the plasma membrane SLC7A3,SLC43A2A,SLC6A6,SLC43A1A,SLC38A3,SLC43A2B,SLC38A5B,SLC1A4,SLC6A19B,SLC38A4
    SLC-mediated transmembrane transport SLC7A3,SLC3A2A,SLC24A5,SLC16A8,SLC22A12,SLC4A2A,SLC26A3,SLC22A7,SLC13A4,SLC43A1B
    Transport of inorganic cations/anions and amino acids/oligopeptides SLC20A2,SLC4A3,SLC3A2A,SLC20A1,SLC15A4,SLC26A7,SLC6A20,SLC7A8A,SLC1A7A,SLC7A6

    Protein Function

    SLC36A2 has several biochemical functions, for example, L-alanine transmembrane transporter activity,L-proline transmembrane transporter activity,glycine transmembrane transporter activity. Some of the functions are cooperated with other proteins, some of the functions could acted by SLC36A2 itself. We selected most functions SLC36A2 had, and list some proteins which have the same functions with SLC36A2. You can find most of the proteins on our site.

    Function Related Protein
    L-alanine transmembrane transporter activity SLC36A3,SLC36A1,SLC1A4,SLC38A7,SLC38A3,SLC36A4
    hydrogen:amino acid symporter activity SLC36A3,SLC36A1
    glycine transmembrane transporter activity SLC36A1,SLC38A5,SLC38A5B,SLC36A3
    hydrogen ion transmembrane transporter activity ATP6V0A1A,SLC36A3,ATP6V0D2,mt-Atp8,ATP5IB,ATP6V1AA,ATP5G3,ATP5G3B,ATP5S,ATP6V1F
    L-proline transmembrane transporter activity SLC6A7,SLC36A1,SLC1A4,SLC36A4,SLC6A20A,SLC36A3

    Interacting Protein

    SLC36A2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SLC36A2 here. Most of them are supplied by our site. Hope this information will be useful for your research of SLC36A2.

    opuD

    Resources

    References

    • Zebisch, K; Brandsch, M; et al. Transport of L-proline by the proton-coupled amino acid transporter PAT2 in differentiated 3T3-L1 cells. AMINO ACIDS 44:373-381(2013).
    • Schioth, HB; Roshanbin, S; et al. Evolutionary origin of amino acid transporter families SLC32, SLC36 and SLC38 and physiological, pathological and therapeutic aspects. MOLECULAR ASPECTS OF MEDICINE 34:571-585(2013).

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