SLC35D1
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Official Full Name
solute carrier family 35 (UDP-glucuronic acid/UDP-N-acetylgalactosamine dual transporter), member D1 -
Overview
Glycosylation of cellular glycoconjugates occurs in the endoplasmic reticulum (ER) and Golgi compartment, and requires transport of nucleotide sugars from the cytosol into the lumen of the ER and Golgi by specific transporters. The protein encoded by this gene resides in the ER, and transports both UDP-glucuronic acid (UDP-GlcA) and UDP-N-acetylgalactosamine (UDP-GalNAc) from the cytoplasm to the ER lumen. It may participate in glucuronidation and/or chondroitin sulfate biosynthesis. Mutations in this gene are associated with Schneckenbecken dysplasia. -
Synonyms
SLC35D1;solute carrier family 35 (UDP-glucuronic acid/UDP-N-acetylgalactosamine dual transporter), member D1;UDP-glucuronic acid/UDP-N-acetylgalactosamine transporter;KIAA0260;UGTREL7;MGC138236;S35D1_HUMAN;Solute carrier family 35 member D1;UDP galactose transporter related 7;UDP-galactose transporter-related protein 7;UDP-GlcA/UDP-GalNAc transporter;UDP-galactose transporter-related 7
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
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| SLC35D1-4276R | Recombinant Rhesus monkey SLC35D1 Protein, His-tagged | Mammalian Cell | Rhesus macaque | His |
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| SLC35D1-4092R | Recombinant Rhesus Macaque SLC35D1 Protein, His (Fc)-Avi-tagged | HEK293 | Rhesus macaque | His&Fc&Avi |
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| SLC35D1-4092R-B | Recombinant Rhesus Macaque SLC35D1 Protein Pre-coupled Magnetic Beads | HEK293 | Rhesus macaque |
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Involved Pathway
SLC35D1 involved in several pathways and played different roles in them. We selected most pathways SLC35D1 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with SLC35D1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
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Protein Function
SLC35D1 has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by SLC35D1 itself. We selected most functions SLC35D1 had, and list some proteins which have the same functions with SLC35D1. You can find most of the proteins on our site.
| Function | Related Protein |
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Interacting Protein
SLC35D1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SLC35D1 here. Most of them are supplied by our site. Hope this information will be useful for your research of SLC35D1.
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References
- Furuichi, T; Dai, J; et al. CANT1 mutation is also responsible for Desbuquois dysplasia, type 2 and Kim variant. JOURNAL OF MEDICAL GENETICS 48:32-37(2011).
- Furuichi, T; Kayserili, H; et al. Identification of loss-of-function mutations of SLC35D1 in patients with Schneckenbecken dysplasia, but not with other severe spondylodysplastic dysplasias group diseases. JOURNAL OF MEDICAL GENETICS 46:562-568(2009).
