SLC30A5

  • Official Full Name

    solute carrier family 30 (zinc transporter), member 5
  • Overview

    This gene encodes a member of the SLC30A/ZnT family of zinc transporter proteins. ZnT proteins mediate both cellular zinc efflux and zinc sequestration into membrane-bound organelles. The encoded protein plays a role in the early secretory pathway as a heterodimer with zinc transporter 6, and may also regulate zinc sequestration into secretory granules of pancreatic beta cells. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 19.
  • Synonyms

    SLC30A5;solute carrier family 30 (zinc transporter), member 5;zinc transporter 5;FLJ12496;FLJ12756;MGC5499;ZnT 5;ZNT5;ZNTL1;ZTL1;DKFZp686F23142;hZTL1;Putative uncharacterized protein DKFZp686F23142;Solute carrier family 30 (zinc transporter) member 5;Solute carrier family 30 (Zinc transporter), member 5 isoform CRA a;Solute carrier family 30 member 5;Zinc transporter ZnT 5;Zinc transporter ZTL1;ZnT-5;ZnT-like transporter 1;ZNT5_HUMAN;ZNTL 1;ZTL 1;OTTHUMP00000161922;OTTHUMP00000221929;OTTHUMP00000223027

Recombinant Proteins

  • Mouse
  • Chicken
  • Rhesus macaque
  • Zebrafish
  • E.coli
  • Mammalian Cell
  • HEK293
  • His
  • His&Fc&Avi
Cat.# Product name Source (Host) Species Tag Protein Length Price
Slc30a5-526M Recombinant Mouse Slc30a5 Protein, His-tagged E.coli Mouse His Asp639~Leu751
SLC30A5-15376M Recombinant Mouse SLC30A5 Protein Mammalian Cell Mouse His
SLC30A5-3069C Recombinant Chicken SLC30A5 Mammalian Cell Chicken His
SLC30A5-4266R Recombinant Rhesus monkey SLC30A5 Protein, His-tagged Mammalian Cell Rhesus macaque His
SLC30A5-471Z Recombinant Zebrafish SLC30A5 Mammalian Cell Zebrafish His
SLC30A5-4082R Recombinant Rhesus Macaque SLC30A5 Protein, His (Fc)-Avi-tagged HEK293 Rhesus macaque His&Fc&Avi
SLC30A5-4082R-B Recombinant Rhesus Macaque SLC30A5 Protein Pre-coupled Magnetic Beads HEK293 Rhesus macaque
SLC30A5-8321M Recombinant Mouse SLC30A5 Protein, His (Fc)-Avi-tagged HEK293 Mouse His&Fc&Avi
SLC30A5-8321M-B Recombinant Mouse SLC30A5 Protein Pre-coupled Magnetic Beads HEK293 Mouse

    Involved Pathway

    SLC30A5 involved in several pathways and played different roles in them. We selected most pathways SLC30A5 participated on our site, such as Insulin processing,Metabolism of proteins,Metal ion SLC transporters, which may be useful for your reference. Also, other proteins which involved in the same pathway with SLC30A5 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds SLC39A14,RHCG2A,RHCGL1,RHBG,SLC30A1B,SLC22A18,SLC22A7A,SLC2A13B,SLC31A1,SLC6A9
    Zinc efflux and compartmentalization by the SLC30 family SLC30A6,SLC30A1A,SLC30A3,SLC30A2,SLC30A8,SLC30A1B
    Metal ion SLC transporters SLC30A2,SLC39A5,SLC39A14,SLC39A3,SLC30A6,SLC30A8,SLC30A1B,SLC30A3,SLC31A1,SLC39A10
    Insulin processing PCSK2,KIF5B,KIF5A,EXOC5,CPE,PCSK1,SLC30A8,EXOC3,EXOC6,SLC30A6
    Metabolism of proteins ARSI,NSMCE2,NAPB,C8orf84,TOMM22,CTSH,LTF,SCMH1,EXOC5,HSCB
    SLC-mediated transmembrane transport SLC35A3A,SLC39A8,SLCO2B1,SLC1A7A,RHCGA,SLC4A3,SLC30A2,SLC15A3,SLC39A7,SLC22A12
    Transmembrane transport of small molecules AQP10A,SLC46A1,SLC14A1,SLC35A3A,TRPC4B,SLC28A3,ANO7,SLC9A7,SLC22A12,PIP
    Peptide hormone metabolism O3far1,SLC30A8,ATP6AP2,CDX2,INHA,CGB5,CPB1,CPE,CMA1,BCHE

    Protein Function

    SLC30A5 has several biochemical functions, for example, cation transmembrane transporter activity,zinc ion transmembrane transporter activity. Some of the functions are cooperated with other proteins, some of the functions could acted by SLC30A5 itself. We selected most functions SLC30A5 had, and list some proteins which have the same functions with SLC30A5. You can find most of the proteins on our site.

    Function Related Protein
    zinc ion transmembrane transporter activity SLC11A2,SLC30A1B,SLC30A10,SLC30A1A,SLC39A1,SLC39A13,SLC39A7,SLC30A7,SLC30A6,SLC39A3
    cation transmembrane transporter activity SLC41A3,SLC30A10,SLC41A1,SLC30A1A,SLC30A7,SLC30A1B,SLC41A2,CHRNE,SLC30A9

    Interacting Protein

    SLC30A5 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SLC30A5 here. Most of them are supplied by our site. Hope this information will be useful for your research of SLC30A5.

    Resources

    References

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