SLC2A3
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Official Full Name
solute carrier family 2 -
Overview
Mammalian cells transport glucose through a family of membrane proteins known as glucose transporters (GLUTs or SLC2A family). Mammalian tissues are known to express different glucose transporter isoforms (exisiting at least GLUTs 1-13) in different tissues. The molecular weight are 40-60 kDa, respectively. GLUT-3 has a high affinity with glucose (Km 1 -5 mM) and is the main transporter in brain (neurons). -
Synonyms
SLC2A3;solute carrier family 2 (facilitated glucose transporter), member 3;GLUT3;GLUT-3;glucose transporter type 3, brain;FLJ90380;SLC2A3;solute carrier family 2
Recombinant Proteins
- Human
- Mouse
- Rhesus macaque
- Rat
- Chicken
- E.coli
- Mammalian Cell
- Wheat Germ
- Insect Cell
- HEK293
- GST
- His
- Non
- His&Flag&Strep
- His&Flag&MBP
- His&Fc&Avi
Involved Pathway
SLC2A3 involved in several pathways and played different roles in them. We selected most pathways SLC2A3 participated on our site, such as Facilitative Na+-independent glucose transporters,Glucose transport,Glycolysis and Gluconeogenesis, which may be useful for your reference. Also, other proteins which involved in the same pathway with SLC2A3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Metabolism | DPYDA.1,UCP3,IVD,UGT1B4,GGT6,FAM36A,SLC25A10,NUDT15,SYT5,ELA2 |
| Facilitative Na+-independent glucose transporters | SLC2A12,SLC2A8,SLC2A6,SLC2A7,SLC2A15A,SLC2A15B,SLC2A10 |
| Metabolism of vitamins and cofactors | GPHN,SLC46A1,KCNG4,GSTO2,CBLC-1,SLC19A2,MMADHC,SLC5A6B,CTRB1,MOCOS |
| Metabolism of carbohydrates | STAB2,AGL,SLC25A12,HS3ST4,Gpc2,SLC26A2,B3GNT2,LYVE1,OXSR1,HAS1 |
| Hexose transport | SLC5A2,SLC5A9,SLC5A4,GCKR |
| Glycolysis and Gluconeogenesis | MPC1,BRP44,DLAT,MPC2,LDHAL6B |
| Metabolism of water-soluble vitamins and cofactors | GSTO2,SLC52A3,TCN1,MOCOS,SLC23A2,SLC25A32,CD320,SLC46A1,CBLC-1,GPHN |
| Glucose transport | GCKR |
Protein Function
SLC2A3 has several biochemical functions, for example, glucose binding,glucose transmembrane transporter activity. Some of the functions are cooperated with other proteins, some of the functions could acted by SLC2A3 itself. We selected most functions SLC2A3 had, and list some proteins which have the same functions with SLC2A3. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| glucose transmembrane transporter activity | SLC2A6,SLC2A4,SLC2A11B,SLC2A11L,SLC2A15A,SLC2A15B,SLC2A1,SLC2A1A,SLC2A9L1,PPBP |
| glucose binding | PYGL,HK3,GYS1,UGP2,SLC2A8,HK1,HKDC1,G6PD,G6PDX,HK2 |
Interacting Protein
SLC2A3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SLC2A3 here. Most of them are supplied by our site. Hope this information will be useful for your research of SLC2A3.
CREB3;GOLGB1;rpoB;q81xc3_bacan;1-phosphatidyl-1d-myo-inositol 3,4,5-trisphosphate
Resources
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References
- Tausendschon, M; Rehli, M; et al. Genome-wide identification of hypoxia-inducible factor-1 and -2 binding sites in hypoxic human macrophages alternatively activated by IL-10. BIOCHIMICA ET BIOPHYSICA ACTA-GENE REGULATORY MECHANISMS 1849:10-22(2015).
- Franca, MR; Mesquita, FS; et al. Modulation of periovulatory endocrine profiles in beef cows: consequences for endometrial glucose transporters and uterine fluid glucose levels. DOMESTIC ANIMAL ENDOCRINOLOGY 50:83-90(2015).
