SLC25A11
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Official Full Name
solute carrier family 25 (mitochondrial carrier; oxoglutarate carrier), member 11 -
Overview
The oxoglutarate/malate carrier transports 2-oxoglutarate across the inner membranes of mitochondria in an;electroneutral exchange for malate or other dicarboxylic acids (summary by Iacobazzi et al., 1992 (PubMed;1457818)). -
Synonyms
SLC25A11;solute carrier family 25 (mitochondrial carrier;oxoglutarate carrier), member 11;SLC20A4;mitochondrial 2-oxoglutarate/malate carrier protein;OGC;OGCP;solute carrier family 25 member 11;solute carrier family 20 (oxoglutarate carrier), memb
Recombinant Proteins
- Human
- Zebrafish
- Rhesus macaque
- Rat
- Mus musculus
- Bovine
- E.coli
- Mammalian Cell
- HEK293
- E.coli expression system
- Insect Cell
- GST
- His
- Non
- His&Flag&MBP
- His&T7
- His&Fc&Avi
Involved Pathway
SLC25A11 involved in several pathways and played different roles in them. We selected most pathways SLC25A11 participated on our site, such as Gluconeogenesis,Glucose metabolism,Metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with SLC25A11 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Metabolism of carbohydrates | SLC26A1,B3GAT2,B3GNT1,B3GNT2,SLC5A9,NHLRC1,ST3GAL3A,B3GNT3,SLC35D2,PYGMB |
| Metabolism | NAALAD2,ACOT9,PNPLA8,ABCA1,BHMT2,CYP3C4,CYP2K16,NHLRC1,ACOT6,MED31 |
| Gluconeogenesis | SLC25A13,SLC25A12,SLC25A10,SLC25A1,SLC25A1A,GPR19 |
| Glucose metabolism | PFKLB,GYG1,GYG1A,NHLRC1,AGL,SLC25A1A,SLC25A12,GYG2,PYGMB,SLC25A13 |
Protein Function
SLC25A11 has several biochemical functions, for example, oxoglutarate:malate antiporter activity,poly(A) RNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SLC25A11 itself. We selected most functions SLC25A11 had, and list some proteins which have the same functions with SLC25A11. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| poly(A) RNA binding | LSM6,NOL11,LSM4,FNDC3B,PTRF,AHNAK,UPF1,PRR3,DHX37,DDX21 |
Interacting Protein
SLC25A11 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SLC25A11 here. Most of them are supplied by our site. Hope this information will be useful for your research of SLC25A11.
TNFRSF1B;CLN3;BABAM1;CDKN1A;COPA;gcvP2;MYC;ICT1;LRRK2;AATK;P;COX15;COA3
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References
- Imai, S; Tokumoto, M; et al. Gene expression differences in the duodenum of 129/Sv and DBA/2 mice compared with that of C57BL/6J mice. JOURNAL OF TOXICOLOGICAL SCIENCES 39:173-177(2014).
- Datta, A; Akatsu, H; et al. Quantitative clinical proteomic study of autopsied human infarcted brain specimens to elucidate the deregulated pathways in ischemic stroke pathology. JOURNAL OF PROTEOMICS 91:556-568(2013).
