SLC24A5
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Official Full Name
solute carrier family 24, member 5 -
Overview
This gene is a member of the potassium-dependent sodium/calcium exchanger family and encodes an intracellular membrane protein with 2 large hydrophilic loops and 2 sets of multiple transmembrane-spanning segments. Sequence variation in this gene has been associated with differences in skin pigmentation. -
Synonyms
SLC24A5;solute carrier family 24, member 5;sodium/potassium/calcium exchanger 5;JSX;Ion transporter JSX;NCKX5;Solute carrier family 24 (sodium/potassium/calcium exchanger),member 5;Solute carrier family 24,member 5;Na(+)/K(+)/Ca(2+)-exchange protein 5;solute carrier family 24 (sodium/potassium/calcium exchanger), member 5;SHEP4
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| SLC24A5-3312C | Recombinant Chicken SLC24A5 | Mammalian Cell | Chicken | His |
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| SLC24A5-3356Z | Recombinant Zebrafish SLC24A5 | Mammalian Cell | Zebrafish | His |
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| SLC24A5-1788HCL | Recombinant Human SLC24A5 293 Cell Lysate | HEK293 | Human | Non |
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Involved Pathway
SLC24A5 involved in several pathways and played different roles in them. We selected most pathways SLC24A5 participated on our site, such as SLC-mediated transmembrane transport,Sodium/Calcium exchangers,Transmembrane transport of small molecules, which may be useful for your reference. Also, other proteins which involved in the same pathway with SLC24A5 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Transmembrane transport of small molecules | SLC12A7,ANKHB,SLC2A13B,RHCG2A,SLC30A6,SLC20A1B,SLC2A15A,TTYH1,SLC9B2,TRPC5A |
| Transport of inorganic cations/anions and amino acids/oligopeptides | SLC20A2,SLC12A3,SLC4A1A,SLC43A1A,SLC6A20,SLC3A2B,SLC6A20B,SLC12A7,SLC15A3,SLC9A6B |
| Sodium/Calcium exchangers | SLC24A6,SLC24A4A,SLC8A2A |
| SLC-mediated transmembrane transport | SLC6A15,SLC10A6,SLC6A6,SLC5A8,SLC39A3,SLC26A6L,SLC39A7,MATE4,SLC39A6,SLC6A20A |
Protein Function
SLC24A5 has several biochemical functions, for example, calcium channel activity,calcium ion binding,calcium, potassium:sodium antiporter activity. Some of the functions are cooperated with other proteins, some of the functions could acted by SLC24A5 itself. We selected most functions SLC24A5 had, and list some proteins which have the same functions with SLC24A5. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| sodium ion binding | SLC24A4A,SLC24A1,SLC24A4,SLC34A2,SLC24A2,PDXK,CAPN3,ATP1A1,SCN9A |
| calcium, potassium:sodium antiporter activity | SLC24A4A,SLC24A4,SLC24A1,SLC24A2 |
| symporter activity | SLC6A13L,SLC6A11A,SLC13A5,SLC5A12,SLC17A6,SLC16A6,SLC1A9,SLC23A1,SLC6A1B,SLC16A12B |
| potassium ion binding | PKM,PDXK,SLC24A2,PKMB,SLC24A4,PKLR,ATP1A1,SLC24A1,SLC24A4A,KCNJ11 |
| calcium channel activity | TRPV6,RYR1,TRPM6,GPM6A,TRPC1,CACNA1SA,SLC24A1,CATSPER2,RYR1B,GRIN2A |
| calcium ion binding | PCDH2AB3,PROS1,THBS4B,NCAN,ANXA11,TMPRSS6,PPP2R3A,CPNE1,NKD2B,ANXA5B |
Interacting Protein
SLC24A5 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SLC24A5 here. Most of them are supplied by our site. Hope this information will be useful for your research of SLC24A5.
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References
- You, JW; Wang, L; et al. Low glucose transporter SLC2A5-inhibited human normal adjacent lung adenocarcinoma cytoplasmic pro-B cell development mechanism network. MOLECULAR AND CELLULAR BIOCHEMISTRY 399:71-76(2015).
- Dickinson, H; Ireland, ZJ; et al. Maternal Dietary Creatine Supplementation Does Not Alter the Capacity for Creatine Synthesis in the Newborn Spiny Mouse. REPRODUCTIVE SCIENCES 20:1096-1102(2013).
