SLC22A7
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Official Full Name
solute carrier family 22 (organic anion transporter), member 7 -
Overview
The protein encoded by this gene is involved in the sodium-independent transport and excretion of organic anions, some of which are potentially toxic. The encoded protein is an integral membrane protein and appears to be localized to the basolateral membrane of the kidney. Alternatively spliced transcript variants encoding different isoforms have been described. -
Synonyms
SLC22A7;solute carrier family 22 (organic anion transporter), member 7;solute carrier family 22 member 7;NLT;OAT2;hOAT2;novel liver transporter;liver-specific transporter;organic anion transporter 2;MGC24091;MGC45202
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| SLC22A7-4305C | Recombinant Chicken SLC22A7 | Mammalian Cell | Chicken | His |
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| SLC22A7-5461R | Recombinant Rat SLC22A7 Protein | Mammalian Cell | Rat | His |
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| SLC22A7-1791HCL | Recombinant Human SLC22A7 293 Cell Lysate | HEK293 | Human | Non |
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| SLC22A7-5120R | Recombinant Rat SLC22A7 Protein, His (Fc)-Avi-tagged | HEK293 | Rat | His&Fc&Avi |
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| SLC22A7-5120R-B | Recombinant Rat SLC22A7 Protein Pre-coupled Magnetic Beads | HEK293 | Rat |
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Involved Pathway
SLC22A7 involved in several pathways and played different roles in them. We selected most pathways SLC22A7 participated on our site, such as Bile secretion,Fluoropyrimidine Activity,Organic anion transport, which may be useful for your reference. Also, other proteins which involved in the same pathway with SLC22A7 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Fluoropyrimidine Activity | DPYS,DHFR,TYMP,DPYD,UPP2,CES1 |
| SLC-mediated transmembrane transport | SLC26A3.2,SLC22A7B.1,SLC5A3A,SLC39A1,SLC30A2,CP,SLC22A12,SLC29A4,PDZD11,SLC4A4A |
| Bile secretion | NR1H4,SLC2A1,HMGCR,SLCO1A6,SLCO1A4,PRKACG,ABCG2,SLC9A1,ATP1A1,SLCO1A2 |
| Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds | SLC2A8,RHCG,SLC22A12,SLC31A1,SLC22A7B.1,SLC39A2,SLC5A9,SLC41A1,SLC22A7A,SLC13A3 |
| Organic cation/anion/zwitterion transport | SLC22A6,SLC22A16,SLC22A7A,SLC22A18,SLC22A15,SLC22A12,SLC22A7B.1 |
| Organic anion transport | SLC22A7A,SLC22A7B.1,SLC22A6,SLC22A12 |
| Transmembrane transport of small molecules | SLC24A6,ABCA4A,CLCN1A,MCOLN3,SLC3A2A,SLC26A3.1,OSTM1,AQP10B,SLC27A4,ANO1 |
Protein Function
SLC22A7 has several biochemical functions, for example, protein binding,sodium-independent organic anion transmembrane transporter activity. Some of the functions are cooperated with other proteins, some of the functions could acted by SLC22A7 itself. We selected most functions SLC22A7 had, and list some proteins which have the same functions with SLC22A7. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| sodium-independent organic anion transmembrane transporter activity | SLCO2A1,SLCO1F4,SLCO1F2,SLCO1A5,SLCO1B3,SLCO1B2,SLCO4C1,SLCO2B1,SLCO1F3,SLC22A12 |
| protein binding | CNIH4,SLC38A2,LIG3,POU1F1,BBS7,MOCS3,HIRA,C7orf53,TAE1,MED29 |
Interacting Protein
SLC22A7 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SLC22A7 here. Most of them are supplied by our site. Hope this information will be useful for your research of SLC22A7.
RAPGEF4;p27958-pro_0000037566
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References
- Ljubojevic, M; Balen, D; et al. Renal expression of organic anion transporter OAT2 in rats and mice is regulated by sex hormones. AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY 292:F361-F372(2007).
