SLC22A12
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Official Full Name
solute carrier family 22 (organic anion/urate transporter), member 12 -
Synonyms
SLC22A12;solute carrier family 22 (organic anion/urate transporter), member 12;solute carrier family 22 (organic anion/cation transporter), member 12;solute carrier family 22 member 12;OAT4L;RST;URAT1;urate transporter 1;urate anion exchanger 1;renal-specific transporter;organic anion transporter 4-like protein
Recombinant Proteins
- Mouse
- Rhesus macaque
- Rat
- Cynomolgus
- Human
- Mammalian Cell
- HEK293
- E.coli
- His
- Non
- His&Fc&Avi
- GST
Involved Pathway
SLC22A12 involved in several pathways and played different roles in them. We selected most pathways SLC22A12 participated on our site, such as Organic anion transport,Organic cation/anion/zwitterion transport,SLC-mediated transmembrane transport, which may be useful for your reference. Also, other proteins which involved in the same pathway with SLC22A12 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Organic anion transport | SLC22A7,SLC22A6,SLC22A7A,SLC22A7B.1 |
| Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds | SLC13A5A,SLC13A1,SLC5A2,RHCG2A,SLC22A16,RHCG,SLC39A3,SLC39A5,SLC6A19A,SLC39A7 |
| Transmembrane transport of small molecules | SLC22A17,MMGT1,SLC30A1A,ABCA4A,BSND,CP,TTYH1,SLC35D1A,ANKH,SLC30A8 |
| Organic cation/anion/zwitterion transport | SLC22A18,SLC22A7B.1,SLC22A15,SLC22A7A,SLC22A16,SLC22A6,SLC22A7 |
| SLC-mediated transmembrane transport | SLC13A2,SLC5A4,SLC29A4,SLC39A5,SLC39A2,SLC35A3,SLC22A15,SLC39A14,SLCO2B1,SLC28A3 |
Protein Function
SLC22A12 has several biochemical functions, for example, PDZ domain binding,inorganic anion exchanger activity,sodium-independent organic anion transmembrane transporter activity. Some of the functions are cooperated with other proteins, some of the functions could acted by SLC22A12 itself. We selected most functions SLC22A12 had, and list some proteins which have the same functions with SLC22A12. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| inorganic anion exchanger activity | SLC22A20,SLC4A1B,SLC4A2B,SLC4A4,SLC4A1,SLC22A8,Slc4a2,SLC22A24,SLC4A3,SLC4A8 |
| PDZ domain binding | CRIPT,NKD1,DOCK4,CXXC4,LNX2,PTENB,GRID2,PLEKHA1,GRM7,TBC1D10A |
| urate transmembrane transporter activity | SLC17A3 |
| sodium-independent organic anion transmembrane transporter activity | SLCO1A6,SLC22A20,SLCO2B1,SLC22A9,SLCO1D1,SLCO1A2,SLCO4C1,SLCO1A4,SLCO4A1,SLCO1C1 |
Interacting Protein
SLC22A12 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SLC22A12 here. Most of them are supplied by our site. Hope this information will be useful for your research of SLC22A12.
NDUFA13
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References
- Joseph, S; Nicolson, TJ; et al. Expression of drug transporters in human kidney: impact of sex, age, and ethnicity. BIOLOGY OF SEX DIFFERENCES 6:-(2015).
- Sun, X; Zhang, R; et al. Common Variants Related to Serum Uric Acid Concentrations Are Associated with Glucose Metabolism and Insulin Secretion in a Chinese Population. PLOS ONE 10:-(2015).
