SLC17A4
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Official Full Name
solute carrier family 17 (sodium phosphate), member 4 -
Overview
Phosphate homeostasis is maintained by regulating intake, intestinal absorption, bone deposition and resorption, and;renal excretion of phosphate. The central molecule in the control of phosphate excretion from the kidney is the;sodium/phosphate cotransporter NPT1 (SLC17A1; MIM 182308), which is located in the renal proximal tubule. NPT1 uses;the transmembrane electrochemical potential gradient of sodium to transport phosphate across the cell membrane.;SLC17A4 is a similar sodium/phosphate cotransporter in the intestinal mucosa that plays an important role in the;absorption of phosphate from the intestine (summary by Shibui et al., 1999 (PubMed 10319585)). -
Synonyms
SLC17A4;solute carrier family 17 (sodium phosphate), member 4;putative small intestine sodium-dependent phosphate transport protein;KAIA2138;KIAA2138;MGC129623;Na/PO4 cotransporter;S17A4_HUMAN;SLC17A4 protein;Solute carrier family 17 (sodium phosphate) member 4;Solute carrier family 17 member 4;9130214H05Rik
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| SLC17A4-15243M | Recombinant Mouse SLC17A4 Protein | Mammalian Cell | Mouse | His |
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| SLC17A4-8241M | Recombinant Mouse SLC17A4 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| SLC17A4-8241M-B | Recombinant Mouse SLC17A4 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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Involved Pathway
SLC17A4 involved in several pathways and played different roles in them. We selected most pathways SLC17A4 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with SLC17A4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
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Protein Function
SLC17A4 has several biochemical functions, for example, sodium-dependent phosphate transmembrane transporter activity,sodium:phosphate symporter activity,symporter activity. Some of the functions are cooperated with other proteins, some of the functions could acted by SLC17A4 itself. We selected most functions SLC17A4 had, and list some proteins which have the same functions with SLC17A4. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| sodium:phosphate symporter activity | SLC17A2,SLC20A2,SLC17A1,SLC34A2,SLC20A1,SLC17A3,SLC34A3 |
| symporter activity | SLC1A9,SLC6A1,SLC6A6B,SLC13A1,SLC6A18,SLC6A4B,SLC17A6A,SLC6A1A,SLC17A5,SLC34A3 |
| sodium-dependent phosphate transmembrane transporter activity | SLC17A2,SLC17A7,SLC17A1,SLC17A3,SLC17A7A,SLC34A3,SLC34A2B,SLC34A2A,SLC34A2 |
Interacting Protein
SLC17A4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SLC17A4 here. Most of them are supplied by our site. Hope this information will be useful for your research of SLC17A4.
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