SLC16A8
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Official Full Name
solute carrier family 16, member 8 (monocarboxylic acid transporter 3) -
Overview
SLC16A8 is a member of a family of proton-coupled monocarboxylate transporters that mediate lactate transport across;cell membranes (Yoon et al., 1999 (PubMed 10493836)). -
Synonyms
SLC16A8;solute carrier family 16, member 8 (monocarboxylic acid transporter 3);solute carrier 16 (monocarboxylic acid transporters), member 8;monocarboxylate transporter 3;MCT3;REMP;MCT 3;Monocarboxylic acid transporter 3;OTTHUMP00000028510;Solute carrier 16 (monocarboxylic acid transporters) member 8;Solute carrier family 16 member 8
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| SLC16A8-11910Z | Recombinant Zebrafish SLC16A8 | Mammalian Cell | Zebrafish | His |
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| SLC16A8-15238M | Recombinant Mouse SLC16A8 Protein | Mammalian Cell | Mouse | His |
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| SLC16A8-6697C | Recombinant Chicken SLC16A8 | Mammalian Cell | Chicken | His |
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| SLC16A8-8238M | Recombinant Mouse SLC16A8 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| SLC16A8-8238M-B | Recombinant Mouse SLC16A8 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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Involved Pathway
SLC16A8 involved in several pathways and played different roles in them. We selected most pathways SLC16A8 participated on our site, such as Basigin interactions,Cell surface interactions at the vascular wall,Hemostasis, which may be useful for your reference. Also, other proteins which involved in the same pathway with SLC16A8 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| SLC-mediated transmembrane transport | SLC15A2,SLC13A5A,SLC5A4,LCN12,SLC28A3,SLC12A7,SLC12A1,RHCGA,SLC12A4,SLC2A15A |
| Pyruvate metabolism and Citric Acid (TCA) cycle | MPC1,SLC16A1,PDPR,D2HGDH,ADHFE1,PDP2,PDK2B,PDP1,PDK3,PDK4 |
| Hemostasis | KIF22,ABHD6B,CD84,KIF4A,PROCA,CFHL3,CEACAM8,HBG1,ZFPM2A,RHOGA |
| Basigin interactions | SLC16A1,SLC7A8A,SLC7A6,BSG,SLC3A2A,SLC7A10,ITGB1B.1,PPIA,NADL1.1,SLC7A11 |
| Metabolism | ADH8A,SLC25A10,CYP26A1,ISCU,DCK,PPM1LB,PDK2B,OAZ2B,AZIN2,TREH |
| Pyruvate metabolism | HAGH,PKMB,ACACA,PCXB,ALDH2.2,PCK1,ACSS2,ME3,ME2,PKMA |
| Proton-coupled monocarboxylate transport | SLC16A7,SLC16A1 |
| Cell surface interactions at the vascular wall | F11R.2,FCER1GL,CEACAM8,DOK2,SLC7A6,MERTK,GLG1B,CXADR,SIRPA,JAM2B |
Protein Function
SLC16A8 has several biochemical functions, for example, lactate transmembrane transporter activity,monocarboxylic acid transmembrane transporter activity,symporter activity. Some of the functions are cooperated with other proteins, some of the functions could acted by SLC16A8 itself. We selected most functions SLC16A8 had, and list some proteins which have the same functions with SLC16A8. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| lactate transmembrane transporter activity | SLC5A12,SLC16A5,SLC16A12,SLC16A7,SLC16A1,SLC16A3,SLC16A12B |
| monocarboxylic acid transmembrane transporter activity | SLC16A4,SLC16A14,SLC16A3,SLCO1A5,SLC16A9A,SLC16A1,SLC16A6A,PPP1R42,SLC16A6,SLC16A9 |
| symporter activity | SLC16A9,MFSD2AA,PPP1R42,SLC1A9,SLC24A4,SLC1A3A,SLC23A1,SLC6A6,SLC5A4,SLC25A22 |
Interacting Protein
SLC16A8 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SLC16A8 here. Most of them are supplied by our site. Hope this information will be useful for your research of SLC16A8.
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