SLC12A4
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Official Full Name
solute carrier family 12 (potassium/chloride transporters), member 4 -
Overview
Potassium-chloride transporter, member 4 is a chloride potassium symporter. It is encoded by the gene SLC12A4. -
Synonyms
SLC12A4;solute carrier family 12 (potassium/chloride transporters), member 4;solute carrier family 12 member 4;KCC1;Electroneutral potassium chloride cotransporter 1;Erythroid K Cl cotransporter 1;FLJ40489;hKCC 1;hKCC1;KCC 1;Potassium transport protein;Potassium/chloride cotransporter 1;Solute carrier family 12 (potassium/chloride transporters) member 4;K-Cl cotransporter;OTTHUMP00000174837;erythroid K:Cl cotransporter;erythroid K-Cl cotransporter 1;electroneutral potassium-chloride cotransporter 1
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| SLC12A4-2698H | Recombinant Human SLC12A4, His-tagged | E.coli | Human | His | C-term-195aa | |
| SLC12A4-5425R | Recombinant Rat SLC12A4 Protein | Mammalian Cell | Rat | His |
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| SLC12A4-1806HCL | Recombinant Human SLC12A4 293 Cell Lysate | HEK293 | Human | Non |
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| SLC12A4-0661H | Recombinant Human SLC12A4 Protein (P2-S1085), 8×His-MBP, Flag tagged | Insect Cell | Human | His&Flag&MBP | P2-S1085 |
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| SLC12A4-5084R | Recombinant Rat SLC12A4 Protein, His (Fc)-Avi-tagged | HEK293 | Rat | His&Fc&Avi |
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| SLC12A4-5084R-B | Recombinant Rat SLC12A4 Protein Pre-coupled Magnetic Beads | HEK293 | Rat |
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Involved Pathway
SLC12A4 involved in several pathways and played different roles in them. We selected most pathways SLC12A4 participated on our site, such as Cation-coupled Chloride cotransporters,SLC-mediated transmembrane transport,Transmembrane transport of small molecules, which may be useful for your reference. Also, other proteins which involved in the same pathway with SLC12A4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Transport of inorganic cations/anions and amino acids/oligopeptides | SLC6A19A,SLC26A3,SLC9A6B,SLC15A1B,SLC4A4A,SLC43A2B,SLC20A1,SLC6A18,SLC9A3.1,SLC17A7A |
| Transmembrane transport of small molecules | TRPC4APA,SLCO3A1,ANKHA,SLC31A1,AQP3A,SLC4A1B,RHCGL1,ABCA4A,SLC22A7B.1,AQP10 |
| Cation-coupled Chloride cotransporters | SLC12A3,SLC12A7,SLC12A5B,SLC12A1 |
| SLC-mediated transmembrane transport | SLC6A20A,SLC16A8,SLC41A1,SLC47A1,SLC6A7,RHCGB,SLC31A1,SLC26A2,SLC5A11,SLC6A2 |
Protein Function
SLC12A4 has several biochemical functions, for example, potassium ion symporter activity,potassium:chloride symporter activity,protein kinase binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SLC12A4 itself. We selected most functions SLC12A4 had, and list some proteins which have the same functions with SLC12A4. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| potassium ion symporter activity | SLC12A7,SLC12A10.2,SLC12A1,SLC12A10.3,SLC12A5,SLC12A2,SLC12A5B,SLC12A10.1,SLC12A8 |
| potassium:chloride symporter activity | SLC12A2,SLC12A10.1,SLC12A7,SLC12A10.2,SLC12A5,SLC12A10.3,SLC12A5B,SLC12A1,SLC12A8 |
| protein kinase binding | CNPPD1,FBXO7,JTB,LAX1,SPDYE2,SPRED1,PKD1,KCNA5,SHC4,TRAF2 |
Interacting Protein
SLC12A4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SLC12A4 here. Most of them are supplied by our site. Hope this information will be useful for your research of SLC12A4.
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