SLA2
-
Official Full Name
Src-like-adaptor 2 -
Overview
This gene encodes a member of the SLAP family of adapter proteins. The encoded protein may play an important receptor-proximal role in downregulating T and B cell-mediated responses and inhibits antigen receptor-induced calcium mobilization. This protein interacts with Cas-Br-M (murine) ecotropic retroviral transforming sequence c. Two transcript variants encoding distinct isoforms have been identified for this gene. -
Synonyms
SLA2;Src-like-adaptor 2;C20orf156;src-like-adapter 2;FLJ21992;SLAP 2;A930009E21Rik;AI430952;MARS;MGC49845;Modulator of antigen receptor signaling;RGD1562071;SLA 2;SLAP2;Src like adapter protein 2;Src like adaptor 2;OTTHUMP00000030867;OTTHUMP00000030868;Src-like adapter protein-2;src-like adapter protein 2;SLAP-2
Recombinant Proteins
- Human
- Rhesus macaque
- Zebrafish
- Mouse
- E.coli
- Mammalian Cell
- HEK293
- HEK293T
- GST
- His
- Non
- His&Fc&Avi
- Myc&DDK
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| SLA2-2692H | Recombinant Human SLA2, GST-tagged | E.coli | Human | GST | 1-261aa | |
| SLA2-2474H | Recombinant human SLA2, His-tagged | E.coli | Human | His |
|
|
| SLA2-4216R | Recombinant Rhesus monkey SLA2 Protein, His-tagged | Mammalian Cell | Rhesus macaque | His |
|
|
| SLA2-6405Z | Recombinant Zebrafish SLA2 | Mammalian Cell | Zebrafish | His |
|
|
| SLA2-1809HCL | Recombinant Human SLA2 293 Cell Lysate | HEK293 | Human | Non |
|
|
| SLA2-1810HCL | Recombinant Human SLA2 293 Cell Lysate | HEK293 | Human | Non |
|
|
| SLA2-4032R | Recombinant Rhesus Macaque SLA2 Protein, His (Fc)-Avi-tagged | HEK293 | Rhesus macaque | His&Fc&Avi |
|
|
| SLA2-4032R-B | Recombinant Rhesus Macaque SLA2 Protein Pre-coupled Magnetic Beads | HEK293 | Rhesus macaque |
|
||
| Sla2-5896M | Recombinant Mouse Sla2 Protein, Myc/DDK-tagged | HEK293T | Mouse | Myc&DDK |
|
Involved Pathway
SLA2 involved in several pathways and played different roles in them. We selected most pathways SLA2 participated on our site, such as B Cell Receptor Signaling Pathway,TCR signaling in naive CD4+ T cells, which may be useful for your reference. Also, other proteins which involved in the same pathway with SLA2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| B Cell Receptor Signaling Pathway | PTPN18,NFATC2,CMTM3,CD72,HRAS,PRKCB,BLK,ITK,CD22,PDK2B |
| TCR signaling in naive CD4+ T cells | DBNL,STK39 |
Protein Function
SLA2 has several biochemical functions, for example, SH3/SH2 adaptor activity,protein N-terminus binding,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SLA2 itself. We selected most functions SLA2 had, and list some proteins which have the same functions with SLA2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | CDK5R2,PITPNM3,SOX13,GOLGA7,RBM3,DPY30,C10orf62,GORASP1,SPI1,CCK |
| SH3/SH2 adaptor activity | ARHGAP1,CHN1,ARHGAP4,CRKL,SH2D3C,BLNK,SH3BGRL,CHN2,SH2D2A,SH2B2 |
| protein N-terminus binding | SDCBP,VPS25,PEX19,GTF2H2,ERCC6,EIF3E,KCNQ2,SNF8,SYNGR3,LACRT |
Interacting Protein
SLA2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SLA2 here. Most of them are supplied by our site. Hope this information will be useful for your research of SLA2.
ERBB2;MET;KIT;GAB1;EGFR;ALB
Resources
Related Services
Related Products
References
