SKIV2L2
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Official Full Name
superkiller viralicidic activity 2-like 2 -
Overview
Superkiller viralicidic activity 2-like 2 is a protein that in humans is encoded by the SKIV2L2 gene. -
Synonyms
SKIV2L2;superkiller viralicidic activity 2-like 2 (S. cerevisiae);KIAA0052;superkiller viralicidic activity 2-like 2;Dob1;fSAP118;functional spliceosome associated protein 118;Mtr4;ATP-dependent helicase SKIV2L2;functional spliceosome-associated
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| SKIV2L2-2690H | Recombinant Human SKIV2L2, His-tagged | E.coli | Human | His | 3-307aa | |
| SKIV2L2-12785Z | Recombinant Zebrafish SKIV2L2 | Mammalian Cell | Zebrafish | His |
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| SKIV2L2-15185M | Recombinant Mouse SKIV2L2 Protein | Mammalian Cell | Mouse | His |
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| SKIV2L2-2156C | Recombinant Chicken SKIV2L2 | Mammalian Cell | Chicken | His |
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| SKIV2L2-8202M | Recombinant Mouse SKIV2L2 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| SKIV2L2-8202M-B | Recombinant Mouse SKIV2L2 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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Involved Pathway
SKIV2L2 involved in several pathways and played different roles in them. We selected most pathways SKIV2L2 participated on our site, such as RNA degradation, which may be useful for your reference. Also, other proteins which involved in the same pathway with SKIV2L2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| RNA degradation | DIS3L,DHX36,TOB1,EXOSC10,DnaK,SMX5,TOB2,EXOSC8,CNOT4,PFKMB |
Protein Function
SKIV2L2 has several biochemical functions, for example, ATP binding,RNA helicase activity,poly(A) RNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SKIV2L2 itself. We selected most functions SKIV2L2 had, and list some proteins which have the same functions with SKIV2L2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| poly(A) RNA binding | CROP,MRPL37,SF1,RPL5A,MRPS14,EXOSC6,RPL23,AGO1,FBL,AKAP1 |
| protein binding | CD164,RBP7,RHNO1,MAGEC2,KCNJ5,NKX2-1,ADAM17,MEP1A,NDUFAF1,NHEJ1 |
| ATP binding | KTI12,FDXACB1,ABCG4B,MLH1,RECQL5,DCK,STK33,PMELA,ERN2,ASS1 |
| RNA helicase activity | UAP1L1,RAD54B,DDX5,FAM120B,DDX24,DHX15,DDX17,CCDC111,CHST13,PRIM2 |
Interacting Protein
SKIV2L2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SKIV2L2 here. Most of them are supplied by our site. Hope this information will be useful for your research of SKIV2L2.
MPHOSPH6;PPP2R2B;YWHAG;PBX2;UPF2;midostaurin;ssrna_ug
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References
- Yoneyama, S; Sakurada, Y; et al. Genetic Variants in the SKIV2L Gene in Exudative Age-related Macular Degeneration in the Japanese Population. OPHTHALMIC GENETICS 35:151-155(2014).
- Lu, F; Shi, Y; et al. A Genetic Variant in the SKIV2L Gene Is Significantly Associated With Age-Related Macular Degeneration in a Han Chinese Population. INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE 54:2911-2917(2013).
