SKIV2L
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Official Full Name
superkiller viralicidic activity 2-like (S. cerevisiae) -
Overview
DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, which is a human homologue of yeast SKI2 and may be involved in antiviral activity by blocking translation of poly(A) deficient mRNAs. This gene is located in the class III region of the major histocompatibility complex. [provided by RefSeq, Jul 2008] -
Synonyms
SKIV2L;superkiller viralicidic activity 2-like (S. cerevisiae);HLP;170A;SKI2;DDX13;SKI2W;SKIV2;THES2;helicase SKI2W;helicase-like protein
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| SKIV2L-2689H | Recombinant Human SKIV2L, GST-tagged | E.coli | Human | GST | C-term-386aa | |
| SKIV2L-4006Z | Recombinant Zebrafish SKIV2L | Mammalian Cell | Zebrafish | His |
|
Involved Pathway
SKIV2L involved in several pathways and played different roles in them. We selected most pathways SKIV2L participated on our site, such as RNA degradation, which may be useful for your reference. Also, other proteins which involved in the same pathway with SKIV2L were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| RNA degradation | RQCD1,CNOT10,BTG4,WDR61,DHX36,MPHOSPH6,PABPC1L2A,CNOT3A,CNOT7,LSM3 |
Protein Function
SKIV2L has several biochemical functions, for example, ATP binding,ATP-dependent RNA helicase activity,RNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SKIV2L itself. We selected most functions SKIV2L had, and list some proteins which have the same functions with SKIV2L. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| RNA binding | METTL14,SAMD4,RBFOX1,LARP6,RPS7,PTBP2B,CELF3A,ASCC1,RBM44,HNRNPF |
| ATP binding | ABCA7,ACTA1,GRK1,MAPKAPK2A,CDK13,ITM2C,ALPK2,KIF17,YME1L1B,CAMKK2 |
| ATP-dependent RNA helicase activity | BAT1,YTHDC2,DHX37,TDRD12,DDX54,DDX3Y,DQX1,DDX59,FAM120B,DDX49 |
Interacting Protein
SKIV2L has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SKIV2L here. Most of them are supplied by our site. Hope this information will be useful for your research of SKIV2L.
WDR61;MYC;WDR1;CDKL5;SNRPB;EXOSC10;q5ngw2_fratt;TSSK2;EXOSC4;CDK11A;KHC;NPM1;Eif3a;RPL10;RAB4B;TTC37;Rpl35;Rrbp1
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References
- Fabre, A; Martinez-Vinson, C; et al. Syndromic diarrhea/Tricho-hepato-enteric syndrome. ORPHANET JOURNAL OF RARE DISEASES 8:-(2013).
