SILV
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Official Full Name
PMEL premelanosome protein -
Overview
This gene encodes a melanocyte-specific type I transmembrane glycoprotein. The encoded protein is enriched in melanosomes, which are the melanin-producing organelles in melanocytes, and plays an essential role in the structural organization of premelanosomes. This protein is involved in generating internal matrix fibers that define the transition from Stage I to Stage II melanosomes. This protein undergoes a complex pattern of prosttranslational processing and modification that is essential to the proper functioning of the protein. A secreted form of this protein that is released by proteolytic ectodomain shedding may be used as a melanoma-specific serum marker. Alternate splicing results in multiple transcript variants. -
Synonyms
P1;SI;SIL;ME20;P100;SILV;ME20M;gp100;ME20-M;PMEL17;D12S53E;melanocyte protein PMEL;melanocyte protein mel 17;silver, mouse, homolog of;melanocyte protein Pmel 17;melanosomal matrix protein17;silver locus protein homolog;melanoma-associated ME20 antigen;melanocytes lineage-specific antigen GP100
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| SILV-2674H | Recombinant Human SILV, GST-tagged | E.coli | Human | GST | 252-593aa | |
| SILV-160H | Recombinant Human Silver Homolog (Mouse) | E.coli | Human | Non | 1-150 a.a. |
|
| SILV-190H | Recombinant Human SILV Protein, MYC/DDK-tagged | HEK293 | Human | Myc&DDK |
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| SILV-1837HCL | Recombinant Human SILV 293 Cell Lysate | HEK293 | Human | Non |
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Involved Pathway
SILV involved in several pathways and played different roles in them. We selected most pathways SILV participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with SILV were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
SILV has several biochemical functions, for example, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SILV itself. We selected most functions SILV had, and list some proteins which have the same functions with SILV. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | SYVN1,CTF1,MRAP,PCK2,TXK,MTA1,ASIC2,PARP9,RIPK1,TRIM22 |
Interacting Protein
SILV has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SILV here. Most of them are supplied by our site. Hope this information will be useful for your research of SILV.
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References
- Song, U; Mun, S; et al. Effects of Three Fire-Suppressant Foams on the Germination and Physiological Responses of Plants. ENVIRONMENTAL MANAGEMENT 54:865-874(2014).
- Kitagawa, RR; Goncalves, RDR; et al. Evaluation of mutagenicity and metabolism-mediated cytotoxicity of the naphthoquinone 5-methoxy-3,4-dehydroxanthomegnin from Paepalanthus latipes Silv., Eriocaulaceae. PLANTA MEDICA 80:1417-1417(2014).
