SHROOM2
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Official Full Name
shroom family member 2 -
Overview
The protein encoded by this gene shares significant similarities with the apical protein from Xenopus laevis which is implicated in amiloride-sensitive sodium channel activity. This gene is a strong candidate gene for ocular albinism type 1 syndrome. -
Synonyms
SHROOM2;shroom family member 2;apical protein, Xenopus laevis like , apical protein like (Xenopus laevis) , APXL;protein Shroom2;4832440C16;Ab2-404;Apical like protein;Apical like protein APXL protein;apical protein of Xenopus-like;Apical protein Xenopus laevis like;apical protein, Xenopus laevis-like;apical protein-like;apical protein-like (Xenopus laevis);Apical-like protein;APX homolog of Xenopus;C630003H05Rik;DKFZp781J074;FLJ39277;HSAPXL;Liver regeneration-related protein LRRG167;OTTHUMP00000022887;Protein Apxl;Shrm2;SHRM2_HUMAN;SHROOM 2;APXL
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| SHROOM2-15116M | Recombinant Mouse SHROOM2 Protein | Mammalian Cell | Mouse | His |
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| SHROOM2-8164M | Recombinant Mouse SHROOM2 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| SHROOM2-8164M-B | Recombinant Mouse SHROOM2 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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Involved Pathway
SHROOM2 involved in several pathways and played different roles in them. We selected most pathways SHROOM2 participated on our site, such as Tight junction, which may be useful for your reference. Also, other proteins which involved in the same pathway with SHROOM2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Tight junction | YBX3,CRB3,MPP5,CLDN15A,JAM2,CLDNF,CTNNA3,CLDN11A,PARD6GA,CLDN2 |
Protein Function
SHROOM2 has several biochemical functions, for example, actin binding,actin filament binding,beta-catenin binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SHROOM2 itself. We selected most functions SHROOM2 had, and list some proteins which have the same functions with SHROOM2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| actin filament binding | WIPF2,SYNE3,VIL1,ANXA8,MYO3A,NEXN,ARPC1A,ACTN4,SMYHC2,EGFR |
| actin binding | MKL1B,AVIL,NEXN,PLEKHH2,CNN1,TMOD2,MYH9A,TMOD3,SNTA1,VMHC |
| protein domain specific binding | HIST1H4K,STX18,DDX20,YWHAE2,NF2,SFN,ODF1,HIST1H4D,PKD1,GSN |
| protein binding | GGA1,TNPO1,AP2A2,MID1,CDK5R1,APEX1,FOXO1,NLGN4X,PDXP,VPS33A |
| beta-catenin binding | PTPRJ,DACT1,DVL3,TAX1BP3,SMAD7,CARM1,MED12L,PARK2,KDM6B,EP300 |
Interacting Protein
SHROOM2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SHROOM2 here. Most of them are supplied by our site. Hope this information will be useful for your research of SHROOM2.
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