SHC4

Official Full Name

SHC (Src homology 2 domain containing) family, member 4
Synonyms

SHC4;SHC (Src homology 2 domain containing) family, member 4;SHC-transforming protein 4;rai like protein;RaLP;hShcD;MGC34023;SH2 domain protein C4;SHC (Src homology 2 domain containing) family member 4;SHC 4;SHC;SHC family member 4;SHC transforming protein 4;SHC transforming protein D;SHCD;Src homology 2 domain containing familymember 4;Src homology 2 domain containing transforming protein C4;rai-like protein;OTTHUMP00000162250;SHC-transforming protein D;src homology 2 domain-containing-transforming protein C4

Recombinant Proteins

Type:

Recombinant Proteins

Cell & Tissue Lysates

Protein Pre-coupled Magnetic Beads

Filters:

Species

Human
Mouse

Source

E.coli
Mammalian Cell
HEK293
HEK293T

Tag

GST
His
Non
Myc&DDK
His&Fc&Avi

Cat.#	Product name	Source (Host)	Species	Tag	Protein Length	Price
SHC4-2656H	Recombinant Human SHC4, GST-tagged	E.coli	Human	GST	C-term-307aa	$319 / 25μg
SHC4-15093M	Recombinant Mouse SHC4 Protein	Mammalian Cell	Mouse	His		Inquiry
SHC4-1861HCL	Recombinant Human SHC4 293 Cell Lysate	HEK293	Human	Non		Inquiry
SHC4-355H	Recombinant Human SHC4 Protein, MYC/DDK-tagged, C13 and N15-labeled	HEK293	Human	Myc&DDK		Inquiry
Shc4-5855M	Recombinant Mouse Shc4 Protein, Myc/DDK-tagged	HEK293T	Mouse	Myc&DDK		Inquiry
SHC4-8144M	Recombinant Mouse SHC4 Protein, His (Fc)-Avi-tagged	HEK293	Mouse	His&Fc&Avi		Inquiry
SHC4-8144M-B	Recombinant Mouse SHC4 Protein Pre-coupled Magnetic Beads	HEK293	Mouse			Inquiry

Involved Pathway

SHC4 involved in several pathways and played different roles in them. We selected most pathways SHC4 participated on our site, such as ErbB signaling pathway,Ras signaling pathway,Chemokine signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with SHC4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
ErbB signaling pathway	STAT5B,SOS1,HBEGFA,STAT5A,MAP2K4,HRAS,MAP2K1,MAP2K2A,PLCG1,NCK2
Glioma	CAMK2B,SHC3,CALM4,IGF1,PRKCA,MTOR,CALM1,CALM3,MAP2K2,PIK3CB
Prolactin signaling pathway	ESR1,FOXO3,AKT1,INS2,PIK3CB,LHCGR,RELA,SOCS4,GALT,PIK3R2
Chronic myeloid leukemia	CBL,AKT1,AKT2,CCND1,NFKBIA,TP53,CRKL,SHC1,PIK3CB,PIK3R5
Chemokine signaling pathway	CCL6,ADRBK2,STAT1,GNB1,STAT2,GNAI3,CCR5,GNG13,CDC42,PIK3CG
Natural killer cell mediated cytotoxicity	GRB2,IFNAR2,KIR2DS4,PIK3CB,PPP3R2,PPP3R1,RAC3,TNFRSF10A,KRAS,MICB
Estrogen signaling pathway	PIK3CD,PIK3R5,HSPA8,HSPA1B,SHC3,FKBP4,MAPK1,KCNJ3,CREB5,CREB3L2
MicroRNAs in cancer	STAT3,KIF23,HNRNPK,MDM4,ERBB2,PLCG1,MDM2,GLS2,SHC1,WNT3
Neurotrophin signaling pathway	MAPK13,MAP2K5,NFKBIE,PIK3R2,PRDM4,HRAS,PDPK1,MAPK3,MAPK7,MAPK12

Protein Function

SHC4 has several biochemical functions, for example, protein binding,protein domain specific binding,protein kinase binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SHC4 itself. We selected most functions SHC4 had, and list some proteins which have the same functions with SHC4. You can find most of the proteins on our site.

Function	Related Protein
receptor tyrosine kinase binding	ARHGEF16,ANXA5,ELMO2,GNB2L1,PTPN2,ANGPT1,TP53,LRP4,PIK3R2,SOCS5
protein domain specific binding	LAMP1,HGS,STAMBP,MPP7,TFDP2,CACNB2,HPCAL4,TNNI3,TACC3,PPARA
protein binding	FOSL2,NATD1,P4HA1,YAP1,SLAMF6,TCERG1,RFWD3,SYNJ2BP,MAP2K5,TXNDC12
protein kinase binding	POLA1,TCTN2,FAM83A,XBP1,CNPPD1,GATA6,EPHA1,AP2A2,SCN5A,SREBF1

Interacting Protein

SHC4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SHC4 here. Most of them are supplied by our site. Hope this information will be useful for your research of SHC4.

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