SHC2

Official Full Name

SHC (Src homology 2 domain containing) transforming protein 2
Overview

SHC-transforming protein 2 is a protein that in humans is encoded by the SHC2 gene, SHC2 has been shown to interact with Kinase insert domain receptor.
Synonyms

SHC2;SHC (Src homology 2 domain containing) transforming protein 2;SHC-transforming protein 2;neuronal Shc adaptor homolog;SCK;SHCB;SLI;Protein Sck;SH2 domain protein C2;SHC transforming protein 2;Src homology 2 domain containing transforming protein C2;SHC-transforming protein B;src homology 2 domain-containing-transforming protein C2

Recombinant Proteins

Type:

Recombinant Proteins

Protein Pre-coupled Magnetic Beads

Filters:

Species

Mouse
Zebrafish
Rat

Source

Mammalian Cell
E.coli
HEK293

Tag

His
His&T7
His&Fc&Avi

Cat.#	Product name	Source (Host)	Species	Tag	Protein Length	Price
SHC2-15091M	Recombinant Mouse SHC2 Protein	Mammalian Cell	Mouse	His		Inquiry
Shc2-1745M	Recombinant Mouse Shc2 protein, His & T7-tagged	E.coli	Mouse	His&T7	Asp98~Glu302	Inquiry
SHC2-4062Z	Recombinant Zebrafish SHC2	Mammalian Cell	Zebrafish	His		Inquiry
SHC2-5390R	Recombinant Rat SHC2 Protein	Mammalian Cell	Rat	His		Inquiry
SHC2-5049R	Recombinant Rat SHC2 Protein, His (Fc)-Avi-tagged	HEK293	Rat	His&Fc&Avi		Inquiry
SHC2-5049R-B	Recombinant Rat SHC2 Protein Pre-coupled Magnetic Beads	HEK293	Rat			Inquiry
SHC2-8142M	Recombinant Mouse SHC2 Protein, His (Fc)-Avi-tagged	HEK293	Mouse	His&Fc&Avi		Inquiry
SHC2-8142M-B	Recombinant Mouse SHC2 Protein Pre-coupled Magnetic Beads	HEK293	Mouse			Inquiry

Involved Pathway

SHC2 involved in several pathways and played different roles in them. We selected most pathways SHC2 participated on our site, such as ErbB signaling pathway,Ras signaling pathway,Chemokine signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with SHC2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Prolactin signaling pathway	SOCS1,MAPK10,PPIB,ESR2,STAT1,IRF1,HRAS,AKT1,INS,NFKB1
Phospholipase D signaling pathway	PLCG2,PTPN11,KIT,PLCB2,AGPAT5,Adcy4,GNAS,PIK3CB,GRM3,PPAP2A
Ras signaling pathway	MET,RALB,RASAL3,PAK2,AKT1,KIT,REL,MAP2K2,PAK3,RASSF1
ErbB signaling pathway	PAK6B,ERBB3A,ERBB4,AKT2,PIK3CA,MYCB,HRASB,AREGB,TGFA,EREG
Glioma	PIK3R2,GRB2,IGF1R,PDGFRB,PIK3CD,BRAF,PLCG2,MAPK1,PIK3CG,SOS1
Natural killer cell mediated cytotoxicity	KLRC2,RAC2,IFNA14,MAPK3,IFNA8,TNFRSF10C,Ifna11,FCGR3B,KIR2DS2,PLCG2
Chemokine signaling pathway	CXCR3,GM10591,PLCB1,RAP1A,CCL8,LYN,ARRB2,Ccl21c,RLN1,PREX1
Chronic myeloid leukemia	NFKBIA,SOS1,CRKL,MAP2K1,CCND1,TP53,CTBP2,HRAS,BCR,CRK
Bacterial invasion of epithelial cells	GAB1,PIK3CA,ARPC4,CTNNA1,DNM2,ELMO1,SEPT1,ACTG1,WASL,CRKL

Protein Function

SHC2 has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by SHC2 itself. We selected most functions SHC2 had, and list some proteins which have the same functions with SHC2. You can find most of the proteins on our site.

Function	Related Protein

Interacting Protein

SHC2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SHC2 here. Most of them are supplied by our site. Hope this information will be useful for your research of SHC2.

ABI1